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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
23.33
Human Site:
S815
Identified Species:
42.78
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S815
P
P
C
K
K
P
L
S
P
V
R
D
N
I
Q
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S815
P
P
C
K
K
P
L
S
P
V
R
D
N
I
Q
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S815
P
S
C
K
K
P
L
S
P
V
R
D
N
I
Q
Dog
Lupus familis
XP_547491
836
92524
S805
C
K
K
P
D
P
L
S
P
V
K
D
N
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
S806
P
S
C
K
K
P
L
S
P
V
K
D
N
I
Q
Rat
Rattus norvegicus
NP_001100668
836
91871
S805
P
S
C
K
K
P
L
S
P
V
K
D
N
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
E804
R
L
T
P
E
T
E
E
E
V
F
N
K
A
E
Chicken
Gallus gallus
XP_419550
807
90135
S776
C
K
K
S
D
P
L
S
P
I
K
D
N
I
Q
Frog
Xenopus laevis
Q9W6K2
734
82213
G718
R
N
N
E
N
V
P
G
L
Q
A
T
I
G
D
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
P782
S
A
T
K
K
G
E
P
M
S
P
V
G
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
N716
K
L
G
A
V
S
Q
N
Q
T
K
L
S
M
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
F719
L
K
P
D
I
S
K
F
G
Y
A
S
S
N
R
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
P686
T
K
S
S
Q
A
R
P
A
V
R
S
I
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
86.6
86.6
N.A.
6.6
53.3
0
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
93.3
93.3
N.A.
26.6
66.6
6.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
0
0
8
0
16
0
0
8
0
% A
% Cys:
16
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
0
0
0
0
0
0
54
0
0
8
% D
% Glu:
0
0
0
8
8
0
16
8
8
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
0
0
8
0
0
8
0
8
8
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
0
16
54
0
% I
% Lys:
8
31
16
47
47
0
8
0
0
0
39
0
8
0
0
% K
% Leu:
8
16
0
0
0
0
54
0
8
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
8
8
0
8
0
0
8
0
0
0
8
54
8
8
% N
% Pro:
39
16
8
16
0
54
8
16
54
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
8
8
0
0
0
0
54
% Q
% Arg:
16
0
0
0
0
0
8
0
0
0
31
0
0
0
8
% R
% Ser:
8
24
8
16
0
16
0
54
0
8
0
16
16
8
0
% S
% Thr:
8
0
16
0
0
8
0
0
0
8
0
8
0
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
62
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _