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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
13.64
Human Site:
T596
Identified Species:
25
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
T596
E
S
S
K
F
T
R
T
I
S
P
P
T
L
G
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
T596
K
S
S
K
F
T
R
T
I
S
P
P
T
L
G
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
T597
K
S
S
K
F
T
R
T
I
S
P
P
T
L
G
Dog
Lupus familis
XP_547491
836
92524
S598
G
T
L
R
N
C
F
S
W
S
G
S
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
A587
E
T
S
K
L
L
G
A
M
S
P
P
S
L
G
Rat
Rattus norvegicus
NP_001100668
836
91871
F600
L
G
T
L
R
S
C
F
S
W
S
G
T
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
S599
F
S
R
T
P
S
P
S
S
D
G
F
F
R
Q
Chicken
Gallus gallus
XP_419550
807
90135
S554
T
E
K
T
K
T
V
S
S
L
P
E
E
R
P
Frog
Xenopus laevis
Q9W6K2
734
82213
L516
I
V
C
N
G
S
A
L
D
I
A
K
E
T
H
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
S579
G
L
G
V
F
S
W
S
G
T
T
K
E
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
Q514
I
F
A
K
E
Q
V
Q
I
R
S
R
F
F
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
M517
A
V
K
T
V
I
N
M
S
S
A
S
K
R
E
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
E484
S
L
E
E
P
V
S
E
S
Q
L
S
T
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
53.3
20
N.A.
6.6
13.3
0
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
73.3
33.3
N.A.
20
20
6.6
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
8
0
0
16
0
0
0
8
% A
% Cys:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% D
% Glu:
16
8
8
8
8
0
0
8
0
0
0
8
24
0
8
% E
% Phe:
8
8
0
0
31
0
8
8
0
0
0
8
16
8
0
% F
% Gly:
16
8
8
0
8
0
8
0
8
0
16
8
0
8
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
16
0
0
0
0
8
0
0
31
8
0
0
0
0
8
% I
% Lys:
16
0
16
39
8
0
0
0
0
0
0
16
8
0
0
% K
% Leu:
8
16
8
8
8
8
0
8
0
8
8
0
8
47
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
16
0
8
0
0
0
39
31
0
0
8
% P
% Gln:
0
0
0
0
0
8
0
8
0
8
0
0
0
8
8
% Q
% Arg:
0
0
8
8
8
0
24
0
0
8
0
8
0
24
0
% R
% Ser:
8
31
31
0
0
31
8
31
39
47
16
24
8
0
0
% S
% Thr:
8
16
8
24
0
31
0
24
0
8
8
0
39
8
0
% T
% Val:
0
16
0
8
8
8
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _