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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
16.97
Human Site:
Y434
Identified Species:
31.11
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
Y434
E
D
D
L
L
S
Q
Y
S
L
S
F
T
K
K
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
Y434
E
D
D
L
L
S
Q
Y
S
L
S
F
M
K
K
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
Y434
E
D
D
L
L
S
Q
Y
S
L
S
F
T
K
K
Dog
Lupus familis
XP_547491
836
92524
Y434
E
D
D
L
L
S
Q
Y
S
L
S
F
T
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
L424
K
R
P
R
N
E
A
L
A
E
D
D
L
L
S
Rat
Rattus norvegicus
NP_001100668
836
91871
Y433
E
D
D
L
L
S
Q
Y
S
S
L
T
K
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
Q434
S
E
D
D
L
L
R
Q
Y
S
F
S
N
T
K
Chicken
Gallus gallus
XP_419550
807
90135
K394
L
P
E
K
S
T
T
K
G
I
E
K
I
I
S
Frog
Xenopus laevis
Q9W6K2
734
82213
D357
H
H
R
S
Q
S
W
D
N
K
Q
L
N
R
K
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
V418
L
P
Q
R
E
S
Q
V
K
R
P
R
E
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
K355
E
K
A
W
P
T
P
K
N
V
K
R
S
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
V358
K
S
F
K
P
E
T
V
K
K
K
L
D
L
P
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
T325
G
F
V
I
H
R
E
T
Q
K
K
Q
I
V
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
0
66.6
N.A.
20
0
13.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
13.3
66.6
N.A.
33.3
20
26.6
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
47
8
0
0
0
8
0
0
8
8
8
8
0
% D
% Glu:
47
8
8
0
8
16
8
0
0
8
8
0
8
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
8
31
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
16
8
8
% I
% Lys:
16
8
0
16
0
0
0
16
16
24
24
8
8
47
47
% K
% Leu:
16
0
0
39
47
8
0
8
0
31
8
16
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
16
0
0
0
16
0
0
% N
% Pro:
0
16
8
0
16
0
8
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
8
0
8
0
47
8
8
0
8
8
0
0
0
% Q
% Arg:
0
8
8
16
0
8
8
0
0
8
0
16
0
8
0
% R
% Ser:
8
8
0
8
8
54
0
0
39
16
31
8
8
0
16
% S
% Thr:
0
0
0
0
0
16
16
8
0
0
0
8
24
8
8
% T
% Val:
0
0
8
0
0
0
0
16
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _