Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK11A All Species: 35.76
Human Site: T514 Identified Species: 65.56
UniProt: Q9UQ88 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ88 NP_076916.2 780 90974 T514 D L K S L M E T M K Q P F L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096048 439 49575 V183 Q P F L P G E V K T L M I Q L
Dog Lupus familis XP_857026 795 92229 T529 D L K S L M E T M K Q P F L P
Cat Felis silvestris
Mouse Mus musculus P24788 784 91495 T518 D L K S L M E T M K Q P F L P
Rat Rattus norvegicus P46892 436 49529 K181 P F L P G E V K T L M I Q L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026042 772 90216 T506 D L K S L M E T M K Q P F L P
Frog Xenopus laevis NP_001086696 788 91927 T522 D L K S L M E T M K Q P F L P
Zebra Danio Brachydanio rerio NP_001008646 800 92940 T534 D L K S L M E T M K Q P F L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPC0 952 108820 T649 D L K S L M E T M K N R K Q S
Honey Bee Apis mellifera XP_625138 840 98674 T567 D L K S L M E T M N Q K K Q V
Nematode Worm Caenorhab. elegans Q09437 719 83549 T448 D M K S L L D T M S R R N K R
Sea Urchin Strong. purpuratus XP_001200924 927 107857 T662 D L K S L M E T M K Q P F T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00546 298 34043 R43 V V A L K K I R L E S E D E G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 55.2 92.1 N.A. 93.7 50.5 N.A. N.A. 89 80.4 74.8 N.A. 41.2 46.9 37.8 46.4
Protein Similarity: 100 N.A. 55.7 94.2 N.A. 95.9 52.9 N.A. N.A. 92.5 87.1 83.7 N.A. 54.2 60.8 55.3 60.7
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 6.6 N.A. N.A. 100 100 100 N.A. 66.6 66.6 40 86.6
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 6.6 N.A. N.A. 100 100 100 N.A. 66.6 66.6 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 77 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 0 0 8 77 0 0 8 0 8 0 8 0 % E
% Phe: 0 8 8 0 0 0 0 0 0 0 0 0 54 0 0 % F
% Gly: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 8 8 0 8 % I
% Lys: 0 0 77 0 8 8 0 8 8 62 0 8 16 8 0 % K
% Leu: 0 70 8 16 77 8 0 0 8 8 8 0 0 54 16 % L
% Met: 0 8 0 0 0 70 0 0 77 0 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 8 0 8 0 0 % N
% Pro: 8 8 0 8 8 0 0 0 0 0 0 54 0 0 47 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 62 0 8 24 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 8 16 0 0 8 % R
% Ser: 0 0 0 77 0 0 0 0 0 8 8 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 77 8 8 0 0 0 8 0 % T
% Val: 8 8 0 0 0 0 8 8 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _