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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK11A All Species: 39.39
Human Site: T580 Identified Species: 72.22
UniProt: Q9UQ88 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ88 NP_076916.2 780 90974 T580 G S P L K A Y T P V V V T Q W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096048 439 49575 T239 G S P L K A Y T P V V V T L W
Dog Lupus familis XP_857026 795 92229 T595 G S P L K A Y T P V V V T L W
Cat Felis silvestris
Mouse Mus musculus P24788 784 91495 T584 G S P L K A Y T P V V V T L W
Rat Rattus norvegicus P46892 436 49529 P237 S P L K A Y T P V V V T L W Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026042 772 90216 T572 G S P L K P Y T P V V V T L W
Frog Xenopus laevis NP_001086696 788 91927 T588 G S P L K P Y T P I V V T L W
Zebra Danio Brachydanio rerio NP_001008646 800 92940 T600 G S P L K P Y T P V V V T L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VPC0 952 108820 T718 G S P I K K Y T S L V V T L W
Honey Bee Apis mellifera XP_625138 840 98674 T636 G S P L R Q Y T P V V V T R W
Nematode Worm Caenorhab. elegans Q09437 719 83549 T517 G D P L K K F T S I V V T L W
Sea Urchin Strong. purpuratus XP_001200924 927 107857 T728 G S P I K P Y T S I V V T L W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00546 298 34043 M99 D L D L K R Y M E G I P K D Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 55.2 92.1 N.A. 93.7 50.5 N.A. N.A. 89 80.4 74.8 N.A. 41.2 46.9 37.8 46.4
Protein Similarity: 100 N.A. 55.7 94.2 N.A. 95.9 52.9 N.A. N.A. 92.5 87.1 83.7 N.A. 54.2 60.8 55.3 60.7
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 93.3 13.3 N.A. N.A. 86.6 80 86.6 N.A. 66.6 80 60 66.6
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 93.3 20 N.A. N.A. 86.6 86.6 86.6 N.A. 80 93.3 73.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 31 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 85 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 16 0 0 0 0 0 24 8 0 0 0 0 % I
% Lys: 0 0 0 8 85 16 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 8 77 0 0 0 0 0 8 0 0 8 70 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 85 0 0 31 0 8 62 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 77 0 0 0 0 0 0 24 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 8 85 0 0 0 8 85 0 0 % T
% Val: 0 0 0 0 0 0 0 0 8 62 93 85 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 85 % W
% Tyr: 0 0 0 0 0 8 85 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _