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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPG7 All Species: 32.73
Human Site: S244 Identified Species: 55.38
UniProt: Q9UQ90 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ90 NP_003110.1 795 88235 S244 A K D R I P V S Y K R T G F F
Chimpanzee Pan troglodytes XP_001140249 795 88440 S244 A K D R I P V S Y K R T G F F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546777 917 101667 S368 G K D R I P V S Y K R T G F F
Cat Felis silvestris
Mouse Mus musculus Q3ULF4 781 85978 S244 S K D R I P V S Y K R T G F F
Rat Rattus norvegicus Q7TT47 744 82104 S244 S K D R I P V S Y K R T G F F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511408 749 83486 S206 G K D R I P V S Y K R T G F F
Chicken Gallus gallus NP_001012545 768 86064 S217 E R E R I P V S Y K H P G F Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923118 788 88169 T235 A K D R I P V T Y K R T G F F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_570017 819 90064 P276 L G I K D G V P V T Y D R Q T
Honey Bee Apis mellifera XP_393770 707 80119 D182 R I G I R M E D G I S I R Y V
Nematode Worm Caenorhab. elegans NP_500191 747 82795 R220 H W T Q I E Y R R S E N V A Q
Sea Urchin Strong. purpuratus XP_001202193 915 101037 D367 Q L G I A H K D R I Q I R Y Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZI8 813 89536 T256 S H D F V P V T Y V S E T I W
Baker's Yeast Sacchar. cerevisiae P40341 825 93258 L284 K D F R I P V L Y V Q E G N W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 N.A. 78.4 N.A. 86.9 82.3 N.A. 80.8 70.5 N.A. 73.9 N.A. 47.8 43.9 43.9 48.2
Protein Similarity: 100 97.3 N.A. 81.7 N.A. 91.4 87.1 N.A. 88.1 83.1 N.A. 84.5 N.A. 64.3 60.3 62.5 62
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 93.3 60 N.A. 93.3 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 93.3 80 N.A. 100 N.A. 13.3 6.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 37.7 39.1 N.A.
Protein Similarity: N.A. N.A. N.A. 57.3 56.4 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 58 0 8 0 0 15 0 0 0 8 0 0 0 % D
% Glu: 8 0 8 0 0 8 8 0 0 0 8 15 0 0 0 % E
% Phe: 0 0 8 8 0 0 0 0 0 0 0 0 0 58 50 % F
% Gly: 15 8 15 0 0 8 0 0 8 0 0 0 65 0 0 % G
% His: 8 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 8 15 72 0 0 0 0 15 0 15 0 8 0 % I
% Lys: 8 50 0 8 0 0 8 0 0 58 0 0 0 0 0 % K
% Leu: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 0 0 0 0 72 0 8 0 0 0 8 0 0 0 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 15 0 0 8 15 % Q
% Arg: 8 8 0 65 8 0 0 8 15 0 50 0 22 0 0 % R
% Ser: 22 0 0 0 0 0 0 50 0 8 15 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 15 0 8 0 50 8 0 8 % T
% Val: 0 0 0 0 8 0 79 0 8 15 0 0 8 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 15 % W
% Tyr: 0 0 0 0 0 0 8 0 72 0 8 0 0 15 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _