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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPG7 All Species: 26.97
Human Site: S330 Identified Species: 45.64
UniProt: Q9UQ90 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ90 NP_003110.1 795 88235 S330 E F V D Y L K S P E R F L Q L
Chimpanzee Pan troglodytes XP_001140249 795 88440 S330 E F V D Y L K S P E R F L Q L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546777 917 101667 S454 E F V D Y L K S P E R F L Q L
Cat Felis silvestris
Mouse Mus musculus Q3ULF4 781 85978 S330 E F V D Y L K S P E R F L Q L
Rat Rattus norvegicus Q7TT47 744 82104 S330 E F V D Y L K S P E R F L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511408 749 83486 S292 E F V D Y L K S P E R F L Q L
Chicken Gallus gallus NP_001012545 768 86064 N303 E F V D Y L K N P D R Y L Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923118 788 88169 N321 E F V D Y L K N P D R Y L Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_570017 819 90064 S362 E F V D Y L K S P E K Y Q R L
Honey Bee Apis mellifera XP_393770 707 80119 N268 E F V D Y L K N P E R Y T K L
Nematode Worm Caenorhab. elegans NP_500191 747 82795 N306 E F V D Y L K N P G R F T K L
Sea Urchin Strong. purpuratus XP_001202193 915 101037 R453 E F V D Y L K R P E K F M E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZI8 813 89536 N348 E F V H F L Q N P K K Y E D L
Baker's Yeast Sacchar. cerevisiae P40341 825 93258 E369 E F V S F L K E P S R Y E K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 N.A. 78.4 N.A. 86.9 82.3 N.A. 80.8 70.5 N.A. 73.9 N.A. 47.8 43.9 43.9 48.2
Protein Similarity: 100 97.3 N.A. 81.7 N.A. 91.4 87.1 N.A. 88.1 83.1 N.A. 84.5 N.A. 64.3 60.3 62.5 62
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 80 N.A. 80 N.A. 73.3 73.3 73.3 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 93.3 93.3 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 37.7 39.1 N.A.
Protein Similarity: N.A. N.A. N.A. 57.3 56.4 N.A.
P-Site Identity: N.A. N.A. N.A. 40 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 86 0 0 0 0 0 15 0 0 0 8 0 % D
% Glu: 100 0 0 0 0 0 0 8 0 65 0 0 15 8 0 % E
% Phe: 0 100 0 0 15 0 0 0 0 0 0 58 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 93 0 0 8 22 0 0 22 0 % K
% Leu: 0 0 0 0 0 100 0 0 0 0 0 0 58 0 93 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % M
% Asn: 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 8 58 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 79 0 0 8 0 % R
% Ser: 0 0 0 8 0 0 0 50 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % T
% Val: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 86 0 0 0 0 0 0 43 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _