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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPG7
All Species:
37.88
Human Site:
S506
Identified Species:
64.1
UniProt:
Q9UQ90
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ90
NP_003110.1
795
88235
S506
T
Q
S
S
T
F
Y
S
Q
R
L
A
E
L
T
Chimpanzee
Pan troglodytes
XP_001140249
795
88440
S506
T
Q
S
S
T
F
Y
S
Q
R
L
A
E
L
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546777
917
101667
S630
T
Q
A
S
S
F
Y
S
Q
R
L
A
E
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULF4
781
85978
S506
T
Q
P
S
S
F
Y
S
Q
R
L
A
E
L
T
Rat
Rattus norvegicus
Q7TT47
744
82104
R473
M
R
P
G
R
L
D
R
H
V
F
I
D
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511408
749
83486
S468
T
Q
T
G
T
F
Y
S
Q
R
L
A
E
L
T
Chicken
Gallus gallus
NP_001012545
768
86064
S479
I
Q
D
A
S
F
Y
S
Q
H
L
A
E
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923118
788
88169
S497
T
Q
P
A
D
F
Y
S
L
R
L
A
E
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570017
819
90064
S540
E
S
P
P
T
T
F
S
Q
R
L
A
R
L
T
Honey Bee
Apis mellifera
XP_393770
707
80119
S444
K
D
K
P
I
K
Y
S
K
Y
L
A
H
L
T
Nematode Worm
Caenorhab. elegans
NP_500191
747
82795
S487
D
H
A
P
Q
E
Y
S
Q
R
L
A
A
L
T
Sea Urchin
Strong. purpuratus
XP_001202193
915
101037
S629
K
G
K
P
A
D
Y
S
T
R
L
A
Q
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
S524
D
H
E
P
S
Y
Y
S
Q
R
L
A
A
L
T
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
K545
A
G
E
I
F
D
L
K
N
R
L
A
A
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
N.A.
78.4
N.A.
86.9
82.3
N.A.
80.8
70.5
N.A.
73.9
N.A.
47.8
43.9
43.9
48.2
Protein Similarity:
100
97.3
N.A.
81.7
N.A.
91.4
87.1
N.A.
88.1
83.1
N.A.
84.5
N.A.
64.3
60.3
62.5
62
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
6.6
N.A.
86.6
66.6
N.A.
73.3
N.A.
53.3
40
53.3
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
20
N.A.
93.3
80
N.A.
80
N.A.
60
46.6
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.7
39.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
56.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
15
8
0
0
0
0
0
0
93
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
8
0
8
15
8
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
15
0
0
8
0
0
0
0
0
0
50
0
0
% E
% Phe:
0
0
0
0
8
50
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
15
0
15
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
15
0
0
0
0
0
0
8
8
0
0
8
0
0
% H
% Ile:
8
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
15
0
15
0
0
8
0
8
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
8
0
8
0
93
0
0
100
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
29
36
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
50
0
0
8
0
0
0
65
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
8
0
0
8
0
79
0
0
8
0
0
% R
% Ser:
0
8
15
29
29
0
0
86
0
0
0
0
0
0
0
% S
% Thr:
43
0
8
0
29
8
0
0
8
0
0
0
0
0
93
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
79
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _