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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPG7 All Species: 39.09
Human Site: S560 Identified Species: 66.15
UniProt: Q9UQ90 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ90 NP_003110.1 795 88235 S560 L A G T A K K S K I L S K E E
Chimpanzee Pan troglodytes XP_001140249 795 88440 S560 L A G T A K K S K I L S K E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546777 917 101667 S684 I A G T A K K S K I L S K E E
Cat Felis silvestris
Mouse Mus musculus Q3ULF4 781 85978 S560 I A G T A K K S K I L S K E E
Rat Rattus norvegicus Q7TT47 744 82104 S523 F S G T A K K S K I L S K E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511408 749 83486 S522 I A G T A K K S K I L S K E E
Chicken Gallus gallus NP_001012545 768 86064 N533 I A G T A K R N K I L S P E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923118 788 88169 S551 I A G S V K K S K I L S K E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_570017 819 90064 S594 V G G T E K R S H A L S L A E
Honey Bee Apis mellifera XP_393770 707 80119 S498 L G G S I K K S S T L T P S E
Nematode Worm Caenorhab. elegans NP_500191 747 82795 S541 L A G S E K R S R S L V E E E
Sea Urchin Strong. purpuratus XP_001202193 915 101037 E683 L A G A A K A E N V M S K E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZI8 813 89536 N578 I G G L E K K N R V I S K L E
Baker's Yeast Sacchar. cerevisiae P40341 825 93258 S599 I G G V E R K S K L L S P E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 N.A. 78.4 N.A. 86.9 82.3 N.A. 80.8 70.5 N.A. 73.9 N.A. 47.8 43.9 43.9 48.2
Protein Similarity: 100 97.3 N.A. 81.7 N.A. 91.4 87.1 N.A. 88.1 83.1 N.A. 84.5 N.A. 64.3 60.3 62.5 62
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 86.6 N.A. 93.3 73.3 N.A. 80 N.A. 46.6 46.6 53.3 60
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 100 93.3 N.A. 93.3 N.A. 60 60 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. 37.7 39.1 N.A.
Protein Similarity: N.A. N.A. N.A. 57.3 56.4 N.A.
P-Site Identity: N.A. N.A. N.A. 40 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 65 0 8 58 0 8 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 29 0 0 8 0 0 0 0 8 79 100 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 29 100 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 50 0 0 0 8 0 0 0 0 58 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 93 72 0 65 0 0 0 65 0 0 % K
% Leu: 36 0 0 8 0 0 0 0 0 8 86 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 22 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 22 0 15 0 0 0 0 0 0 % R
% Ser: 0 8 0 22 0 0 0 79 8 8 0 86 0 8 0 % S
% Thr: 0 0 0 58 0 0 0 0 0 8 0 8 0 0 0 % T
% Val: 8 0 0 8 8 0 0 0 0 15 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _