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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPG7
All Species:
20.91
Human Site:
T499
Identified Species:
35.38
UniProt:
Q9UQ90
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ90
NP_003110.1
795
88235
T499
H
L
K
S
L
K
L
T
Q
S
S
T
F
Y
S
Chimpanzee
Pan troglodytes
XP_001140249
795
88440
T499
H
L
K
S
L
K
L
T
Q
S
S
T
F
Y
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546777
917
101667
T623
H
L
K
S
L
K
L
T
Q
A
S
S
F
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULF4
781
85978
T499
H
L
K
G
L
K
L
T
Q
P
S
S
F
Y
S
Rat
Rattus norvegicus
Q7TT47
744
82104
M466
D
V
L
D
N
A
L
M
R
P
G
R
L
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511408
749
83486
T461
H
L
K
S
L
K
L
T
Q
T
G
T
F
Y
S
Chicken
Gallus gallus
NP_001012545
768
86064
I472
H
L
K
G
L
K
L
I
Q
D
A
S
F
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923118
788
88169
T490
H
L
K
I
L
K
L
T
Q
P
A
D
F
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570017
819
90064
E533
H
L
S
S
V
K
L
E
S
P
P
T
T
F
S
Honey Bee
Apis mellifera
XP_393770
707
80119
K437
H
L
Q
S
L
L
L
K
D
K
P
I
K
Y
S
Nematode Worm
Caenorhab. elegans
NP_500191
747
82795
D480
Y
M
R
K
I
K
L
D
H
A
P
Q
E
Y
S
Sea Urchin
Strong. purpuratus
XP_001202193
915
101037
K622
Y
L
K
K
L
V
L
K
G
K
P
A
D
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
D517
Y
L
K
K
I
K
L
D
H
E
P
S
Y
Y
S
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
A538
H
L
H
H
L
K
L
A
G
E
I
F
D
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
N.A.
78.4
N.A.
86.9
82.3
N.A.
80.8
70.5
N.A.
73.9
N.A.
47.8
43.9
43.9
48.2
Protein Similarity:
100
97.3
N.A.
81.7
N.A.
91.4
87.1
N.A.
88.1
83.1
N.A.
84.5
N.A.
64.3
60.3
62.5
62
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
6.6
N.A.
86.6
66.6
N.A.
73.3
N.A.
46.6
46.6
26.6
40
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
20
N.A.
93.3
80
N.A.
80
N.A.
60
53.3
60
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.7
39.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
56.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
15
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
15
8
8
0
8
15
8
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
15
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
50
8
0
% F
% Gly:
0
0
0
15
0
0
0
0
15
0
15
0
0
0
0
% G
% His:
72
0
8
8
0
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
15
0
0
8
0
0
8
8
0
0
0
% I
% Lys:
0
0
65
22
0
79
0
15
0
15
0
0
8
0
8
% K
% Leu:
0
86
8
0
72
8
100
0
0
0
0
0
8
8
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
29
36
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
50
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
8
% R
% Ser:
0
0
8
43
0
0
0
0
8
15
29
29
0
0
86
% S
% Thr:
0
0
0
0
0
0
0
43
0
8
0
29
8
0
0
% T
% Val:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
22
0
0
0
0
0
0
0
0
0
0
0
8
79
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _