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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AURKC All Species: 38.48
Human Site: S243 Identified Species: 65.13
UniProt: Q9UQB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQB9 NP_001015878.1 309 35591 S243 Y P P F E S A S H S E T Y R R
Chimpanzee Pan troglodytes XP_001142357 309 35587 S243 Y P P F E S A S H S E T Y R R
Rhesus Macaque Macaca mulatta XP_001098364 471 52859 S405 Y P P F E S T S H S E T Y R R
Dog Lupus familis XP_849906 346 39574 S279 N P P F E S A S H N E T Y R R
Cat Felis silvestris
Mouse Mus musculus O88445 282 32888 T216 K P P F E S S T S S E T Y R R
Rat Rattus norvegicus O55099 343 39216 S280 N P P F E S P S H S E T Y R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521399 303 34973 T232 K P P F E A E T Y Q E T Y R S
Chicken Gallus gallus XP_425725 409 46456 T347 K P P F E A Q T Y Q E T Y R A
Frog Xenopus laevis Q6GPL3 368 41997 S300 M P P F D S P S H S E T H R R
Zebra Danio Brachydanio rerio Q6NW76 320 36928 S253 N P P F E T A S H A E T Y K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKN7 329 38282 S255 C P P F E S N S T E S T Y S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01427 305 34731 D230 K P P F E H E D Q S K T Y A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q683C9 282 32738 E218 V P P F E A R E H S E T Y K R
Baker's Yeast Sacchar. cerevisiae P38991 367 42927 M305 A P P F E E E M K D T T Y K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 63.4 70.5 N.A. 72.4 67.3 N.A. 64.7 52.3 58.1 65.3 N.A. 43.1 N.A. 54.6 N.A.
Protein Similarity: 100 100 64.7 78.9 N.A. 82.5 79.3 N.A. 78.3 62.3 71.1 78.7 N.A. 62.6 N.A. 68.9 N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 86.6 N.A. 53.3 53.3 73.3 73.3 N.A. 53.3 N.A. 46.6 N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 73.3 73.3 86.6 93.3 N.A. 60 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 56.3 38.6 N.A.
Protein Similarity: N.A. N.A. N.A. 70.8 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 22 29 0 0 8 0 0 0 8 15 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 93 8 22 8 0 8 79 0 0 0 0 % E
% Phe: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 58 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 29 0 0 0 0 0 0 0 8 0 8 0 0 22 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 22 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 100 100 0 0 0 15 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 15 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 65 72 % R
% Ser: 0 0 0 0 0 58 8 58 8 58 8 0 0 8 8 % S
% Thr: 0 0 0 0 0 8 8 22 8 0 8 100 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 22 0 0 0 0 0 0 0 15 0 0 0 93 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _