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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAB2 All Species: 7.88
Human Site: Y491 Identified Species: 17.33
UniProt: Q9UQC2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQC2 NP_036428.1 676 74458 Y491 H H F D S L G Y P S T T L P V
Chimpanzee Pan troglodytes XP_525517 686 74573 Q485 P T L P A V K Q A G D D S Q G
Rhesus Macaque Macaca mulatta XP_001093917 677 74423 Y492 H H F D S L G Y P S T T L P M
Dog Lupus familis XP_542285 762 83533 Y577 H H F E G L S Y P S T A L S M
Cat Felis silvestris
Mouse Mus musculus Q9Z1S8 665 73190 L485 L G Y P S T A L P I H R G P S
Rat Rattus norvegicus Q9EQH1 665 73310 L485 L G Y P S T A L P I H R G P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513247 815 89872 M578 F D F S S F G M Q V P P P A H
Chicken Gallus gallus XP_001234549 681 75233 L490 H H F D L V G L S S A T L P M
Frog Xenopus laevis NP_001089201 691 76011 A508 P R R S V P S A D C E P P P V
Zebra Danio Brachydanio rerio XP_692935 666 73590 G486 A T L P A R K G S T A S L C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ9 878 95517 A637 R Y D F M E Q A D C P P V N R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.5 98.8 83 N.A. 91.7 91.2 N.A. 33.2 78.1 38.6 63 N.A. 20.9 N.A. N.A. N.A.
Protein Similarity: 100 73.7 99.5 85.9 N.A. 93.6 93.7 N.A. 46.5 87.6 56 74.4 N.A. 37.8 N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 60 N.A. 20 20 N.A. 20 60 13.3 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 73.3 N.A. 26.6 26.6 N.A. 20 73.3 13.3 33.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 19 0 19 19 10 0 19 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 0 0 0 10 0 % C
% Asp: 0 10 10 28 0 0 0 0 19 0 10 10 0 0 0 % D
% Glu: 0 0 0 10 0 10 0 0 0 0 10 0 0 0 0 % E
% Phe: 10 0 46 10 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 10 0 37 10 0 10 0 0 19 0 10 % G
% His: 37 37 0 0 0 0 0 0 0 0 19 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % K
% Leu: 19 0 19 0 10 28 0 28 0 0 0 0 46 0 10 % L
% Met: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 28 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 19 0 0 37 0 10 0 0 46 0 19 28 19 55 0 % P
% Gln: 0 0 0 0 0 0 10 10 10 0 0 0 0 10 0 % Q
% Arg: 10 10 10 0 0 10 0 0 0 0 0 19 0 0 10 % R
% Ser: 0 0 0 19 46 0 19 0 19 37 0 10 10 10 19 % S
% Thr: 0 19 0 0 0 19 0 0 0 10 28 28 0 0 0 % T
% Val: 0 0 0 0 10 19 0 0 0 10 0 0 10 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 19 0 0 0 0 28 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _