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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCN8A
All Species:
22.73
Human Site:
S594
Identified Species:
50
UniProt:
Q9UQD0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQD0
NP_055006.1
1980
225280
S594
E
H
S
T
V
E
E
S
E
G
R
R
D
S
L
Chimpanzee
Pan troglodytes
XP_001141985
1976
224859
S594
E
H
S
T
V
E
E
S
E
G
R
R
D
S
L
Rhesus Macaque
Macaca mulatta
XP_001090295
1980
225320
S594
E
H
S
T
V
E
E
S
E
G
R
R
D
S
L
Dog
Lupus familis
XP_850134
1980
225167
S594
E
H
S
T
V
E
E
S
E
G
R
R
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTU3
1978
225123
S594
E
H
S
T
V
E
E
S
E
G
R
R
D
S
L
Rat
Rattus norvegicus
O88420
1978
225141
S594
E
H
S
T
V
E
E
S
E
G
R
R
D
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512721
2008
228348
N606
E
H
S
T
F
E
D
N
D
S
R
R
D
S
L
Chicken
Gallus gallus
XP_424477
1978
225428
G592
S
T
V
E
E
S
E
G
R
R
D
S
L
F
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q20JQ7
1784
201644
C534
Q
E
D
I
E
R
P
C
P
P
G
W
Y
K
F
Tiger Blowfish
Takifugu rubipres
Q2XVR7
1892
213080
A551
R
S
A
S
V
A
T
A
A
A
S
V
A
T
A
Fruit Fly
Dros. melanogaster
P35500
2131
239344
L657
S
Y
T
S
H
G
D
L
L
G
G
M
A
V
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
99.9
99.3
N.A.
98.4
98.5
N.A.
76.9
94.2
N.A.
61.9
61.6
44.3
N.A.
N.A.
N.A.
Protein Similarity:
100
97.1
99.9
99.6
N.A.
99.4
99.4
N.A.
86.8
97
N.A.
73.8
73.4
61.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
66.6
6.6
N.A.
0
6.6
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
13.3
N.A.
6.6
33.3
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
10
10
10
0
0
19
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
19
0
10
0
10
0
64
0
0
% D
% Glu:
64
10
0
10
19
64
64
0
55
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
10
0
10
0
64
19
0
0
0
0
% G
% His:
0
64
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
10
10
64
64
0
0
0
% R
% Ser:
19
10
64
19
0
10
0
55
0
10
10
10
0
64
0
% S
% Thr:
0
10
10
64
0
0
10
0
0
0
0
0
0
10
0
% T
% Val:
0
0
10
0
64
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _