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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
25.45
Human Site:
S1067
Identified Species:
40
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
S1067
G
D
V
E
G
S
Q
S
Q
D
E
G
E
G
S
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
S1224
G
D
V
E
G
S
Q
S
Q
D
E
G
E
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
S1078
G
D
V
E
G
S
Q
S
Q
D
E
G
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
S1067
G
D
V
E
G
S
Q
S
Q
D
E
G
E
G
S
Rat
Rattus norvegicus
P97690
1191
138430
K1034
E
A
I
Q
L
T
F
K
Q
V
S
K
N
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
S1088
G
D
V
E
G
S
Q
S
Q
D
E
G
E
G
S
Chicken
Gallus gallus
Q90988
1189
134923
V1037
L
H
I
A
W
E
K
V
N
K
D
F
G
S
I
Frog
Xenopus laevis
O93309
1209
140704
K1059
K
A
T
L
V
M
K
K
G
D
V
E
G
S
Q
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
S1067
G
D
T
E
G
G
Q
S
Q
D
E
G
E
G
G
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
S1067
G
D
A
E
G
S
Q
S
Q
D
E
G
E
S
G
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
G1050
F
K
K
L
V
P
M
G
A
G
F
L
I
L
K
Honey Bee
Apis mellifera
XP_393700
1202
139436
H1052
K
K
L
V
P
S
G
H
A
Q
L
V
M
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
E650
D
T
R
K
S
R
L
E
L
Q
S
G
I
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
K1020
V
I
E
E
L
D
E
K
K
K
E
T
L
K
V
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
H1079
K
N
D
N
A
N
D
H
D
E
S
I
D
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
0
6.6
80
80
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
100
20
13.3
80
80
0
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
7
7
0
0
0
14
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
47
7
0
0
7
7
0
7
54
7
0
7
0
7
% D
% Glu:
7
0
7
54
0
7
7
7
0
7
54
7
47
0
7
% E
% Phe:
7
0
0
0
0
0
7
0
0
0
7
7
0
7
0
% F
% Gly:
47
0
0
0
47
7
7
7
7
7
0
54
14
40
14
% G
% His:
0
7
0
0
0
0
0
14
0
0
0
0
0
0
0
% H
% Ile:
0
7
14
0
0
0
0
0
0
0
0
7
14
0
7
% I
% Lys:
20
14
7
7
0
0
14
20
7
14
0
7
0
14
7
% K
% Leu:
7
0
7
14
14
0
7
0
7
0
7
7
7
7
0
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
7
0
7
0
0
7
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
47
0
54
14
0
0
0
0
7
% Q
% Arg:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
47
0
47
0
0
20
0
0
20
40
% S
% Thr:
0
7
14
0
0
7
0
0
0
0
0
7
0
0
7
% T
% Val:
7
0
34
7
14
0
0
7
0
7
7
7
0
14
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _