KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK8IP1
All Species:
19.09
Human Site:
S425
Identified Species:
52.5
UniProt:
Q9UQF2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQF2
NP_005447.1
711
77524
S425
S
V
S
S
P
Y
E
S
A
I
G
E
E
Y
E
Chimpanzee
Pan troglodytes
XP_001160866
711
77562
S425
S
V
S
S
P
Y
E
S
A
I
G
E
E
Y
E
Rhesus Macaque
Macaca mulatta
XP_001113132
702
77286
S416
S
V
S
S
P
Y
E
S
A
I
G
E
E
Y
E
Dog
Lupus familis
XP_540760
606
67622
S339
P
R
P
S
A
C
L
S
E
D
S
T
P
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVI9
707
77264
S421
S
A
S
S
P
Y
E
S
A
I
G
E
E
Y
E
Rat
Rattus norvegicus
Q9R237
708
77300
S422
S
A
S
S
P
Y
E
S
A
I
G
E
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421126
604
67559
S337
K
R
D
S
V
C
L
S
E
D
S
T
P
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919760
735
82699
A451
E
D
D
E
D
Q
E
A
D
E
E
D
E
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0K0
490
53797
Q223
S
P
D
S
E
R
M
Q
S
L
G
D
V
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.6
79.7
N.A.
93.9
94.2
N.A.
N.A.
61.8
N.A.
40.6
N.A.
27.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95
80.8
N.A.
95.6
95.6
N.A.
N.A.
68.9
N.A.
54.9
N.A.
41.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
26.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
12
0
0
12
56
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
34
0
12
0
0
0
12
23
0
23
0
23
0
% D
% Glu:
12
0
0
12
12
0
67
0
23
12
12
56
67
23
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
56
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
23
0
0
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
12
0
56
0
0
0
0
0
0
0
23
0
0
% P
% Gln:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
23
0
0
0
12
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
0
56
89
0
0
0
78
12
0
23
0
0
0
23
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% T
% Val:
0
34
0
0
12
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
56
0
0
0
0
0
0
0
56
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _