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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMK2A All Species: 11.21
Human Site: S318 Identified Species: 22.42
UniProt: Q9UQM7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQM7 NP_741960.1 478 54030 S318 R N F S G G K S G G N K K S D
Chimpanzee Pan troglodytes XP_001164869 479 54199 V319 R N F S G R H V A L Q R E G E
Rhesus Macaque Macaca mulatta XP_001096460 479 54071 Q319 R N F S G G S Q G G D K K P D
Dog Lupus familis XP_853581 478 54087 S318 R N F S G G K S G G N K K N D
Cat Felis silvestris
Mouse Mus musculus Q6PHZ2 499 56351 K318 T R N F S A A K S L L K K P D
Rat Rattus norvegicus P11275 478 54096 S318 R N F S G G K S G G N K K N D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510250 634 71113 K474 K K N D G V K K R K S S S S V
Chicken Gallus gallus Q5ZKI0 479 54184 K318 T R N F S A A K S L L K K P D
Frog Xenopus laevis Q9DG02 475 53914 K316 A T R N F S A K S L L K K P D
Zebra Danio Brachydanio rerio Q6DEH3 491 55810 T331 G V K E P Q T T V I H N P T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 S361 D R S T T V V S K E P E D I R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 M367 R M K Q F R A M N K L K K L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 88.5 99.5 N.A. 83.5 99.7 N.A. 73.8 87 86.6 84.1 N.A. 70.3 N.A. N.A. N.A.
Protein Similarity: 100 96 95.1 99.7 N.A. 90.1 100 N.A. 74.6 93.9 94.3 90.8 N.A. 80.3 N.A. N.A. N.A.
P-Site Identity: 100 33.3 73.3 93.3 N.A. 20 93.3 N.A. 20 20 20 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 53.3 80 100 N.A. 20 100 N.A. 33.3 20 26.6 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 17 34 0 9 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 0 0 0 0 0 9 0 9 0 67 % D
% Glu: 0 0 0 9 0 0 0 0 0 9 0 9 9 0 9 % E
% Phe: 0 0 42 17 17 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 50 34 0 0 34 34 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % I
% Lys: 9 9 17 0 0 0 34 34 9 17 0 67 67 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 34 34 0 0 9 0 % L
% Met: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 42 25 9 0 0 0 0 9 0 25 9 0 17 0 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 9 0 9 34 0 % P
% Gln: 0 0 0 9 0 9 0 9 0 0 9 0 0 0 0 % Q
% Arg: 50 25 9 0 0 17 0 0 9 0 0 9 0 0 9 % R
% Ser: 0 0 9 42 17 9 9 34 25 0 9 9 9 17 0 % S
% Thr: 17 9 0 9 9 0 9 9 0 0 0 0 0 9 0 % T
% Val: 0 9 0 0 0 17 9 9 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _