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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP2B All Species: 17.88
Human Site: S187 Identified Species: 24.58
UniProt: Q9UQN3 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQN3 NP_054762.2 213 23907 S187 K A P S A A R S L P S A S T S
Chimpanzee Pan troglodytes XP_001173977 89 9836 S70 S L P S A S T S K A T I S D E
Rhesus Macaque Macaca mulatta XP_001104442 213 23833 S187 K A P S A A G S L P S A S T S
Dog Lupus familis XP_544799 793 86557 S767 K A P S A A R S L P S A S T S
Cat Felis silvestris
Mouse Mus musculus Q8BJF9 213 23916 S187 K A P S A A R S L P S A S T S
Rat Rattus norvegicus Q8CGS4 223 25043 P189 S K V T D A L P E P E P A G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515189 417 46084 G390 K A P S A A R G L P S A S S S
Chicken Gallus gallus Q5F3A2 214 24041 G187 K A P S A A R G L P S A S T S
Frog Xenopus laevis Q7SYR0 214 23832 G187 K A P S A A K G L P S A S A S
Zebra Danio Brachydanio rerio Q6NXD2 214 23998 K187 H A P S A A R K T P S A A T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647947 212 23810 S189 S I P A T G S S D F E T S G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493357 207 23149 K186 N V P A L P T K V S S T A P A
Sea Urchin Strong. purpuratus XP_001187930 222 24218 A197 D A P G Y K G A L P S R A S D
Poplar Tree Populus trichocarpa XP_002300769 212 23254 A187 A A P K G K I A G K N R E N A
Maize Zea mays NP_001148635 212 23345 A187 S A P K G K I A G K K V Q V D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q941D5 210 23008 G187 S A P K G K I G G K K A E D V
Baker's Yeast Sacchar. cerevisiae P36108 232 26272 S192 S T P Q N L V S N A P I A E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.7 98.5 26.7 N.A. 99.5 25.5 N.A. 49.8 94.3 90.6 84.1 N.A. 48.8 N.A. 43.1 45.5
Protein Similarity: 100 41.7 99 26.8 N.A. 100 52.9 N.A. 50.3 96.2 95.7 92.5 N.A. 69 N.A. 61.5 63
P-Site Identity: 100 33.3 93.3 100 N.A. 100 13.3 N.A. 86.6 93.3 80 66.6 N.A. 20 N.A. 13.3 33.3
P-Site Similarity: 100 46.6 93.3 100 N.A. 100 33.3 N.A. 93.3 93.3 86.6 80 N.A. 26.6 N.A. 40 53.3
Percent
Protein Identity: 34.2 36.6 N.A. 35.6 29.7 N.A.
Protein Similarity: 62.9 63.3 N.A. 61 54.3 N.A.
P-Site Identity: 13.3 13.3 N.A. 20 13.3 N.A.
P-Site Similarity: 33.3 20 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 71 0 12 53 53 0 18 0 12 0 53 30 6 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 6 0 0 0 6 0 0 0 0 12 12 % D
% Glu: 0 0 0 0 0 0 0 0 6 0 12 0 12 6 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % F
% Gly: 0 0 0 6 18 6 12 24 18 0 0 0 0 12 0 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 6 0 0 0 0 18 0 0 0 0 12 0 0 0 % I
% Lys: 42 6 0 18 0 24 6 12 6 18 12 0 0 0 6 % K
% Leu: 0 6 0 0 6 6 6 0 48 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 0 6 0 0 0 6 0 6 0 0 6 0 % N
% Pro: 0 0 95 0 0 6 0 6 0 59 6 6 0 6 0 % P
% Gln: 0 0 0 6 0 0 0 0 0 0 0 0 6 0 0 % Q
% Arg: 0 0 0 0 0 0 36 0 0 0 0 12 0 0 0 % R
% Ser: 36 0 0 53 0 6 6 42 0 6 59 0 53 12 42 % S
% Thr: 0 6 0 6 6 0 12 0 6 0 6 12 0 36 6 % T
% Val: 0 6 6 0 0 0 6 0 6 0 0 6 0 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _