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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP2B All Species: 26.06
Human Site: S192 Identified Species: 35.83
UniProt: Q9UQN3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQN3 NP_054762.2 213 23907 S192 A R S L P S A S T S K A T I S
Chimpanzee Pan troglodytes XP_001173977 89 9836 S75 S T S K A T I S D E E I E R Q
Rhesus Macaque Macaca mulatta XP_001104442 213 23833 S192 A G S L P S A S T S K A T I S
Dog Lupus familis XP_544799 793 86557 S772 A R S L P S A S T S K A T I S
Cat Felis silvestris
Mouse Mus musculus Q8BJF9 213 23916 S192 A R S L P S A S T S K A T I S
Rat Rattus norvegicus Q8CGS4 223 25043 A194 A L P E P E P A G A M A A S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515189 417 46084 S395 A R G L P S A S S S K A A T I
Chicken Gallus gallus Q5F3A2 214 24041 S192 A R G L P S A S T S K A S T I
Frog Xenopus laevis Q7SYR0 214 23832 S192 A K G L P S A S A S K S T G I
Zebra Danio Brachydanio rerio Q6NXD2 214 23998 A192 A R K T P S A A T A K A D G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647947 212 23810 S194 G S S D F E T S G K R T E K D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493357 207 23149 A191 P T K V S S T A P A D F D D L
Sea Urchin Strong. purpuratus XP_001187930 222 24218 A202 K G A L P S R A S D S Q A K D
Poplar Tree Populus trichocarpa XP_002300769 212 23254 E192 K I A G K N R E N A S S S G I
Maize Zea mays NP_001148635 212 23345 Q192 K I A G K K V Q V D G S S E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q941D5 210 23008 E192 K I G G K K A E D V G S S G I
Baker's Yeast Sacchar. cerevisiae P36108 232 26272 A197 L V S N A P I A E T A M G I P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.7 98.5 26.7 N.A. 99.5 25.5 N.A. 49.8 94.3 90.6 84.1 N.A. 48.8 N.A. 43.1 45.5
Protein Similarity: 100 41.7 99 26.8 N.A. 100 52.9 N.A. 50.3 96.2 95.7 92.5 N.A. 69 N.A. 61.5 63
P-Site Identity: 100 13.3 93.3 100 N.A. 100 20 N.A. 66.6 73.3 60 53.3 N.A. 13.3 N.A. 6.6 20
P-Site Similarity: 100 33.3 93.3 100 N.A. 100 33.3 N.A. 73.3 80 73.3 66.6 N.A. 20 N.A. 26.6 40
Percent
Protein Identity: 34.2 36.6 N.A. 35.6 29.7 N.A.
Protein Similarity: 62.9 63.3 N.A. 61 54.3 N.A.
P-Site Identity: 0 0 N.A. 6.6 13.3 N.A.
P-Site Similarity: 33.3 20 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 53 0 18 0 12 0 53 30 6 24 6 48 18 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 12 12 6 0 12 6 12 % D
% Glu: 0 0 0 6 0 12 0 12 6 6 6 0 12 6 6 % E
% Phe: 0 0 0 0 6 0 0 0 0 0 0 6 0 0 0 % F
% Gly: 6 12 24 18 0 0 0 0 12 0 12 0 6 24 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 18 0 0 0 0 12 0 0 0 0 6 0 30 36 % I
% Lys: 24 6 12 6 18 12 0 0 0 6 48 0 0 12 0 % K
% Leu: 6 6 0 48 0 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 6 6 0 0 0 % M
% Asn: 0 0 0 6 0 6 0 0 6 0 0 0 0 0 0 % N
% Pro: 6 0 6 0 59 6 6 0 6 0 0 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 6 % Q
% Arg: 0 36 0 0 0 0 12 0 0 0 6 0 0 6 0 % R
% Ser: 6 6 42 0 6 59 0 53 12 42 12 24 24 6 24 % S
% Thr: 0 12 0 6 0 6 12 0 36 6 0 6 30 12 0 % T
% Val: 0 6 0 6 0 0 6 0 6 6 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _