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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP2B
All Species:
13.64
Human Site:
S199
Identified Species:
18.75
UniProt:
Q9UQN3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQN3
NP_054762.2
213
23907
S199
S
T
S
K
A
T
I
S
D
E
E
I
E
R
Q
Chimpanzee
Pan troglodytes
XP_001173977
89
9836
Q82
S
D
E
E
I
E
R
Q
L
K
A
L
G
V
D
Rhesus Macaque
Macaca mulatta
XP_001104442
213
23833
S199
S
T
S
K
A
T
I
S
D
E
E
I
E
R
Q
Dog
Lupus familis
XP_544799
793
86557
S779
S
T
S
K
A
T
I
S
D
E
E
I
E
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJF9
213
23916
S199
S
T
S
K
A
T
I
S
D
E
E
I
E
R
Q
Rat
Rattus norvegicus
Q8CGS4
223
25043
E201
A
G
A
M
A
A
S
E
G
D
E
E
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515189
417
46084
I402
S
S
S
K
A
A
T
I
S
D
E
E
I
E
R
Chicken
Gallus gallus
Q5F3A2
214
24041
I199
S
T
S
K
A
S
T
I
S
D
E
E
I
E
R
Frog
Xenopus laevis
Q7SYR0
214
23832
I199
S
A
S
K
S
T
G
I
S
D
E
E
I
E
R
Zebra Danio
Brachydanio rerio
Q6NXD2
214
23998
I199
A
T
A
K
A
D
G
I
S
D
E
D
I
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647947
212
23810
D201
S
G
K
R
T
E
K
D
I
A
D
Q
L
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493357
207
23149
L198
A
P
A
D
F
D
D
L
E
A
Q
L
A
R
L
Sea Urchin
Strong. purpuratus
XP_001187930
222
24218
D209
A
S
D
S
Q
A
K
D
K
A
I
E
D
Q
L
Poplar Tree
Populus trichocarpa
XP_002300769
212
23254
I199
E
N
A
S
S
S
G
I
D
E
L
E
K
R
L
Maize
Zea mays
NP_001148635
212
23345
L199
Q
V
D
G
S
S
E
L
E
E
L
E
K
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q941D5
210
23008
I199
E
D
V
G
S
S
G
I
D
E
L
E
K
R
L
Baker's Yeast
Sacchar. cerevisiae
P36108
232
26272
P204
A
E
T
A
M
G
I
P
E
P
I
G
A
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.7
98.5
26.7
N.A.
99.5
25.5
N.A.
49.8
94.3
90.6
84.1
N.A.
48.8
N.A.
43.1
45.5
Protein Similarity:
100
41.7
99
26.8
N.A.
100
52.9
N.A.
50.3
96.2
95.7
92.5
N.A.
69
N.A.
61.5
63
P-Site Identity:
100
6.6
100
100
N.A.
100
13.3
N.A.
33.3
40
33.3
26.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
46.6
N.A.
53.3
60
53.3
53.3
N.A.
26.6
N.A.
40
26.6
Percent
Protein Identity:
34.2
36.6
N.A.
35.6
29.7
N.A.
Protein Similarity:
62.9
63.3
N.A.
61
54.3
N.A.
P-Site Identity:
20
13.3
N.A.
20
6.6
N.A.
P-Site Similarity:
46.6
40
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
6
24
6
48
18
0
0
0
18
6
0
12
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
6
0
12
6
12
36
30
6
6
12
6
6
% D
% Glu:
12
6
6
6
0
12
6
6
18
42
53
48
24
24
6
% E
% Phe:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
12
0
6
24
0
6
0
0
6
6
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
6
0
30
36
6
0
12
24
24
0
0
% I
% Lys:
0
0
6
48
0
0
12
0
6
6
0
0
18
0
6
% K
% Leu:
0
0
0
0
0
0
0
12
6
0
18
12
6
0
30
% L
% Met:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
6
0
0
0
0
0
6
0
6
0
0
0
0
0
% P
% Gln:
6
0
0
0
6
0
0
6
0
0
6
6
0
6
24
% Q
% Arg:
0
0
0
6
0
0
6
0
0
0
0
0
0
48
24
% R
% Ser:
53
12
42
12
24
24
6
24
24
0
0
0
0
0
6
% S
% Thr:
0
36
6
0
6
30
12
0
0
0
0
0
0
0
0
% T
% Val:
0
6
6
0
0
0
0
0
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _