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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A13
All Species:
26.36
Human Site:
S122
Identified Species:
58
UniProt:
Q9Y226
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y226
NP_004247.2
551
60862
S122
Y
P
E
N
R
L
P
S
L
K
N
E
F
N
L
Chimpanzee
Pan troglodytes
XP_526175
551
60843
S122
Y
P
E
N
R
L
P
S
L
K
N
E
F
N
L
Rhesus Macaque
Macaca mulatta
XP_001087330
551
61004
S122
Y
P
E
N
R
L
P
S
L
K
N
E
F
N
L
Dog
Lupus familis
XP_542706
551
60793
S122
Y
P
E
H
G
P
L
S
L
Q
N
E
F
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4L0
551
60722
S122
Y
P
E
N
R
P
Q
S
L
K
K
E
F
D
L
Rat
Rattus norvegicus
O35956
551
60748
S118
Y
D
N
S
T
F
P
S
T
I
V
T
E
W
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521203
462
51596
S46
L
A
L
P
S
M
I
S
P
F
F
F
F
G
Q
Chicken
Gallus gallus
XP_418529
539
59592
S120
Y
P
T
A
Q
Q
P
S
L
L
T
E
F
D
L
Frog
Xenopus laevis
Q66J54
558
62434
S123
Y
S
K
D
E
F
N
S
T
I
I
T
E
W
D
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
T127
N
M
T
E
M
S
S
T
I
I
T
E
W
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
S115
D
R
S
K
Y
L
N
S
A
V
T
E
W
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
80.9
N.A.
73.1
34.4
N.A.
47.3
48
34.7
34.8
N.A.
36.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
96.5
88.7
N.A.
84
55.5
N.A.
58.9
67.1
56
53.3
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
73.3
20
N.A.
13.3
53.3
13.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
26.6
N.A.
20
66.6
26.6
40
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
0
0
0
0
0
0
0
28
10
% D
% Glu:
0
0
46
10
10
0
0
0
0
0
0
73
19
0
0
% E
% Phe:
0
0
0
0
0
19
0
0
0
10
10
10
64
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
28
10
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
0
37
10
0
0
0
0
% K
% Leu:
10
0
10
0
0
37
10
0
55
10
0
0
0
0
73
% L
% Met:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
37
0
0
19
0
0
0
37
0
0
46
10
% N
% Pro:
0
55
0
10
0
19
46
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
10
0
0
10
0
0
0
0
10
% Q
% Arg:
0
10
0
0
37
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
10
10
10
10
91
0
0
0
0
0
0
0
% S
% Thr:
0
0
19
0
10
0
0
10
19
0
28
19
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
19
19
0
% W
% Tyr:
73
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _