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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A13
All Species:
11.52
Human Site:
S522
Identified Species:
25.33
UniProt:
Q9Y226
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y226
NP_004247.2
551
60862
S522
E
L
G
P
H
P
R
S
P
K
S
V
P
S
E
Chimpanzee
Pan troglodytes
XP_526175
551
60843
S522
E
L
G
P
H
P
R
S
P
K
S
V
P
S
E
Rhesus Macaque
Macaca mulatta
XP_001087330
551
61004
S522
E
L
G
P
H
P
W
S
P
K
S
V
P
S
E
Dog
Lupus familis
XP_542706
551
60793
P522
D
Q
G
P
H
P
R
P
P
G
S
A
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4L0
551
60722
S522
E
Q
G
L
P
A
G
S
H
K
T
A
P
Q
R
Rat
Rattus norvegicus
O35956
551
60748
L519
L
P
D
T
V
Q
D
L
K
S
R
S
R
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521203
462
51596
L434
F
P
V
L
I
T
V
L
A
V
I
G
K
F
A
Chicken
Gallus gallus
XP_418529
539
59592
T511
E
L
P
D
G
T
E
T
D
N
P
Q
R
R
S
Frog
Xenopus laevis
Q66J54
558
62434
I528
I
E
E
V
E
K
R
I
K
A
P
K
K
E
N
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
G531
I
Q
D
I
D
D
R
G
L
A
R
T
N
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
G518
M
P
E
T
I
E
D
G
E
N
F
G
K
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.4
80.9
N.A.
73.1
34.4
N.A.
47.3
48
34.7
34.8
N.A.
36.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
96.5
88.7
N.A.
84
55.5
N.A.
58.9
67.1
56
53.3
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
33.3
0
N.A.
0
13.3
6.6
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
40
6.6
N.A.
0
20
6.6
20
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
19
0
19
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
10
10
10
19
0
10
0
0
0
0
0
0
% D
% Glu:
46
10
19
0
10
10
10
0
10
0
0
0
0
10
37
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
46
0
10
0
10
19
0
10
0
19
0
10
0
% G
% His:
0
0
0
0
37
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
19
0
0
10
19
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
19
37
0
10
28
10
19
% K
% Leu:
10
37
0
19
0
0
0
19
10
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
19
0
0
10
0
10
% N
% Pro:
0
28
10
37
10
37
0
10
37
0
19
0
46
0
10
% P
% Gln:
0
28
0
0
0
10
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
46
0
0
0
19
0
19
10
10
% R
% Ser:
0
0
0
0
0
0
0
37
0
10
37
10
0
46
10
% S
% Thr:
0
0
0
19
0
19
0
10
0
0
10
10
0
0
0
% T
% Val:
0
0
10
10
10
0
10
0
0
10
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _