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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD4
All Species:
31.52
Human Site:
S188
Identified Species:
63.03
UniProt:
Q9Y227
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y227
NP_001122402.1
616
70255
S188
G
M
R
I
L
P
E
S
Q
Q
K
A
I
L
E
Chimpanzee
Pan troglodytes
XP_519659
710
80224
S290
G
M
R
I
L
P
E
S
Q
Q
K
A
I
L
E
Rhesus Macaque
Macaca mulatta
XP_001108472
728
82237
S308
G
M
R
I
L
P
E
S
Q
Q
K
A
I
L
E
Dog
Lupus familis
XP_543243
608
69462
S188
G
M
R
I
L
P
E
S
Q
Q
K
A
I
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT4
613
69727
S188
G
M
R
V
L
P
E
S
Q
Q
K
A
I
L
E
Rat
Rattus norvegicus
P97687
511
57389
E114
E
C
M
K
M
S
T
E
R
I
P
A
S
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
S204
G
M
R
I
L
P
E
S
Q
Q
K
A
I
L
E
Chicken
Gallus gallus
P79784
495
54515
L98
G
K
S
L
E
H
C
L
S
Q
A
M
R
D
V
Frog
Xenopus laevis
NP_001088548
616
70594
S188
G
L
R
I
L
T
E
S
Q
Q
E
A
I
L
E
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
S188
G
M
R
V
L
P
E
S
Q
Q
E
A
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
K155
N
L
R
N
K
L
P
K
I
T
S
M
Q
V
L
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
P139
L
A
E
L
A
S
T
P
S
E
A
S
I
Y
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
82.2
93.5
N.A.
93
26.4
N.A.
86.5
24.5
77.1
70.6
N.A.
N.A.
N.A.
30.6
48.5
Protein Similarity:
100
85.4
82.8
96.4
N.A.
97.5
47.4
N.A.
92
42.6
88.4
84.2
N.A.
N.A.
N.A.
48.8
63.3
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
100
13.3
80
80
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
20
93.3
100
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
17
75
0
0
0
% A
% Cys:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
9
0
9
0
67
9
0
9
17
0
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
50
0
0
0
0
9
9
0
0
67
0
0
% I
% Lys:
0
9
0
9
9
0
0
9
0
0
50
0
0
9
0
% K
% Leu:
9
17
0
17
67
9
0
9
0
0
0
0
9
67
9
% L
% Met:
0
59
9
0
9
0
0
0
0
0
0
17
0
0
9
% M
% Asn:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
59
9
9
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
67
75
0
0
9
0
9
% Q
% Arg:
0
0
75
0
0
0
0
0
9
0
0
0
9
0
0
% R
% Ser:
0
0
9
0
0
17
0
67
17
0
9
9
9
0
0
% S
% Thr:
0
0
0
0
0
9
17
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _