KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD4
All Species:
14.24
Human Site:
Y281
Identified Species:
28.48
UniProt:
Q9Y227
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y227
NP_001122402.1
616
70255
Y281
G
V
S
T
Q
I
A
Y
E
V
P
K
T
V
S
Chimpanzee
Pan troglodytes
XP_519659
710
80224
G375
T
A
G
I
L
D
M
G
G
V
S
T
Q
I
A
Rhesus Macaque
Macaca mulatta
XP_001108472
728
82237
G393
T
A
G
I
L
D
M
G
G
V
S
T
Q
I
A
Dog
Lupus familis
XP_543243
608
69462
G273
T
A
G
I
L
D
M
G
G
V
S
T
Q
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT4
613
69727
Y281
G
V
S
T
Q
I
A
Y
E
V
P
Q
T
V
S
Rat
Rattus norvegicus
P97687
511
57389
E192
L
L
G
R
F
T
Q
E
Q
S
W
L
N
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
Y297
G
V
S
T
Q
I
A
Y
E
V
P
K
T
V
S
Chicken
Gallus gallus
P79784
495
54515
N176
T
A
N
Y
L
L
E
N
F
I
K
R
G
W
L
Frog
Xenopus laevis
NP_001088548
616
70594
Y281
G
V
S
T
Q
I
A
Y
E
V
P
K
S
V
S
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
G273
T
A
G
V
L
D
M
G
G
V
S
T
Q
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
S233
L
P
D
T
D
S
F
S
S
I
N
V
E
N
I
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
V217
I
S
G
K
Q
E
G
V
Y
A
W
I
G
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
82.2
93.5
N.A.
93
26.4
N.A.
86.5
24.5
77.1
70.6
N.A.
N.A.
N.A.
30.6
48.5
Protein Similarity:
100
85.4
82.8
96.4
N.A.
97.5
47.4
N.A.
92
42.6
88.4
84.2
N.A.
N.A.
N.A.
48.8
63.3
P-Site Identity:
100
6.6
6.6
6.6
N.A.
93.3
0
N.A.
100
0
93.3
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
20
20
20
N.A.
100
13.3
N.A.
100
26.6
100
20
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
0
0
34
0
0
9
0
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
34
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
9
9
34
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
9
0
9
0
9
0
0
0
0
9
0
% F
% Gly:
34
0
50
0
0
0
9
34
34
0
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
25
0
34
0
0
0
17
0
9
0
42
17
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
9
25
0
0
0
% K
% Leu:
17
9
0
0
42
9
0
0
0
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
0
0
9
0
9
9
9
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
34
0
0
0
0
% P
% Gln:
0
0
0
0
42
0
9
0
9
0
0
9
34
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
34
0
0
9
0
9
9
9
34
0
9
0
34
% S
% Thr:
42
0
0
42
0
9
0
0
0
0
0
34
25
0
0
% T
% Val:
0
34
0
9
0
0
0
9
0
67
0
9
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
0
0
9
0
% W
% Tyr:
0
0
0
9
0
0
0
34
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _