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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUVBL2
All Species:
29.09
Human Site:
S181
Identified Species:
49.23
UniProt:
Q9Y230
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y230
NP_006657.1
463
51157
S181
L
G
T
K
M
I
E
S
L
T
K
D
K
V
Q
Chimpanzee
Pan troglodytes
XP_001172016
429
47386
K170
K
A
T
G
K
I
S
K
L
G
R
S
F
T
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533625
463
51124
S181
L
G
T
K
M
I
E
S
L
T
K
D
K
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTM5
463
51094
S181
L
G
T
K
M
I
E
S
L
T
K
D
K
V
Q
Rat
Rattus norvegicus
P60123
456
50195
S179
L
D
P
S
I
F
E
S
L
Q
K
E
R
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9DE27
462
51169
S180
L
G
T
K
M
I
E
S
L
T
K
E
K
V
Q
Zebra Danio
Brachydanio rerio
P83571
463
51232
S181
L
G
T
K
M
I
E
S
L
S
K
E
R
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3K3
481
53523
C177
L
G
N
K
I
I
E
C
F
M
K
E
K
I
Q
Honey Bee
Apis mellifera
XP_001122537
462
51397
S180
L
G
N
K
M
I
D
S
L
M
K
E
K
V
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323491
467
51574
S178
L
G
A
K
M
I
E
S
L
G
K
E
K
V
Q
Maize
Zea mays
NP_001148563
478
52214
A192
L
G
G
K
M
I
E
A
L
G
K
E
K
V
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201564
469
52095
A178
M
G
A
K
M
I
E
A
L
N
K
E
K
V
Q
Baker's Yeast
Sacchar. cerevisiae
Q12464
471
51593
G178
L
G
N
K
M
I
D
G
L
T
K
E
K
V
L
Red Bread Mold
Neurospora crassa
Q873C7
481
52225
A179
M
G
S
K
M
I
D
A
M
T
K
E
R
V
M
Conservation
Percent
Protein Identity:
100
92.4
N.A.
99.7
N.A.
99.5
42.5
N.A.
N.A.
N.A.
93.9
88.3
N.A.
74.2
83.3
N.A.
N.A.
Protein Similarity:
100
92.4
N.A.
100
N.A.
99.7
66
N.A.
N.A.
N.A.
98.6
97.4
N.A.
85.8
93
N.A.
N.A.
P-Site Identity:
100
20
N.A.
100
N.A.
100
40
N.A.
N.A.
N.A.
93.3
80
N.A.
53.3
73.3
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
66.6
N.A.
N.A.
N.A.
100
100
N.A.
73.3
86.6
N.A.
N.A.
Percent
Protein Identity:
73.4
70
N.A.
73.9
66.4
65
Protein Similarity:
87.7
85.5
N.A.
88.4
82.5
81.5
P-Site Identity:
80
73.3
N.A.
66.6
66.6
46.6
P-Site Similarity:
86.6
86.6
N.A.
86.6
80
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
0
0
22
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
22
0
0
0
0
22
0
0
0
% D
% Glu:
0
0
0
0
0
0
72
0
0
0
0
72
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
86
8
8
0
0
0
8
0
22
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
93
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
86
8
0
0
8
0
0
93
0
72
0
0
% K
% Leu:
79
0
0
0
0
0
0
0
86
0
0
0
0
0
8
% L
% Met:
15
0
0
0
79
0
0
0
8
15
0
0
0
0
8
% M
% Asn:
0
0
22
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
72
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
22
0
8
% R
% Ser:
0
0
8
8
0
0
8
58
0
8
0
8
0
0
0
% S
% Thr:
0
0
43
0
0
0
0
0
0
43
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _