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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUVBL2
All Species:
29.09
Human Site:
T388
Identified Species:
49.23
UniProt:
Q9Y230
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y230
NP_006657.1
463
51157
T388
E
M
S
E
D
A
Y
T
V
L
T
R
I
G
L
Chimpanzee
Pan troglodytes
XP_001172016
429
47386
T354
E
M
S
E
D
A
Y
T
V
L
T
R
I
G
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533625
463
51124
T388
E
M
S
E
D
A
Y
T
V
L
T
R
I
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTM5
463
51094
T388
E
M
S
E
D
A
Y
T
V
L
T
R
I
G
L
Rat
Rattus norvegicus
P60123
456
50195
A379
K
Q
I
I
K
I
R
A
Q
T
E
G
I
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9DE27
462
51169
T387
D
M
S
E
D
A
Y
T
V
L
T
R
I
G
L
Zebra Danio
Brachydanio rerio
P83571
463
51232
T388
E
L
S
E
E
A
H
T
V
L
T
R
I
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3K3
481
53523
T384
I
M
H
P
D
A
L
T
I
L
T
R
I
A
T
Honey Bee
Apis mellifera
XP_001122537
462
51397
T387
E
M
A
D
D
A
L
T
V
L
T
R
I
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323491
467
51574
A385
E
M
A
E
E
A
K
A
L
L
T
H
I
G
V
Maize
Zea mays
NP_001148563
478
52214
V399
E
M
S
A
D
A
K
V
L
L
T
K
I
G
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201564
469
52095
Q385
E
M
N
E
E
A
K
Q
L
L
T
L
I
G
R
Baker's Yeast
Sacchar. cerevisiae
Q12464
471
51593
D385
E
L
S
S
D
A
L
D
L
L
T
K
T
G
V
Red Bread Mold
Neurospora crassa
Q873C7
481
52225
A386
D
L
T
P
D
A
L
A
L
L
T
K
I
G
A
Conservation
Percent
Protein Identity:
100
92.4
N.A.
99.7
N.A.
99.5
42.5
N.A.
N.A.
N.A.
93.9
88.3
N.A.
74.2
83.3
N.A.
N.A.
Protein Similarity:
100
92.4
N.A.
100
N.A.
99.7
66
N.A.
N.A.
N.A.
98.6
97.4
N.A.
85.8
93
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
N.A.
N.A.
93.3
73.3
N.A.
53.3
73.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
N.A.
N.A.
100
93.3
N.A.
60
86.6
N.A.
N.A.
Percent
Protein Identity:
73.4
70
N.A.
73.9
66.4
65
Protein Similarity:
87.7
85.5
N.A.
88.4
82.5
81.5
P-Site Identity:
53.3
60
N.A.
53.3
46.6
40
P-Site Similarity:
80
80
N.A.
73.3
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
0
93
0
22
0
0
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
8
72
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
72
0
0
58
22
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
79
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
8
8
0
8
0
0
8
0
0
0
93
0
8
% I
% Lys:
8
0
0
0
8
0
22
0
0
0
0
22
0
0
0
% K
% Leu:
0
22
0
0
0
0
29
0
36
93
0
8
0
0
43
% L
% Met:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
58
0
0
8
% R
% Ser:
0
0
58
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
58
0
8
93
0
8
0
8
% T
% Val:
0
0
0
0
0
0
0
8
50
0
0
0
0
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _