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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUVBL2 All Species: 45.45
Human Site: Y430 Identified Species: 76.92
UniProt: Q9Y230 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y230 NP_006657.1 463 51157 Y430 V D D I K R V Y S L F L D E S
Chimpanzee Pan troglodytes XP_001172016 429 47386 Y396 V D D I K R V Y S L F L D E S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533625 463 51124 Y430 V D D I K R V Y S L F L D E S
Cat Felis silvestris
Mouse Mus musculus Q9WTM5 463 51094 Y430 V D D I K R V Y S L F L D E S
Rat Rattus norvegicus P60123 456 50195 G421 N L L A K I N G K D S I E K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE27 462 51169 Y429 V D D I K R V Y S L F L D E S
Zebra Danio Brachydanio rerio P83571 463 51232 Y430 V E D I K R V Y S L F L D E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3K3 481 53523 Y426 T E D V K K V Y S L F L D E N
Honey Bee Apis mellifera XP_001122537 462 51397 Y429 I D D V K R V Y S L F L D E N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323491 467 51574 Y427 S E D I T R V Y N L F L D V K
Maize Zea mays NP_001148563 478 52214 Y441 M E D I S R V Y Q L F L D V K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_201564 469 52095 Y427 V E D I Q R V Y R L F L D V R
Baker's Yeast Sacchar. cerevisiae Q12464 471 51593 Y427 V E D V K R A Y L L F L D S A
Red Bread Mold Neurospora crassa Q873C7 481 52225 F428 V E D V Q R S F K L F Y D P A
Conservation
Percent
Protein Identity: 100 92.4 N.A. 99.7 N.A. 99.5 42.5 N.A. N.A. N.A. 93.9 88.3 N.A. 74.2 83.3 N.A. N.A.
Protein Similarity: 100 92.4 N.A. 100 N.A. 99.7 66 N.A. N.A. N.A. 98.6 97.4 N.A. 85.8 93 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 6.6 N.A. N.A. N.A. 100 86.6 N.A. 66.6 80 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 26.6 N.A. N.A. N.A. 100 100 N.A. 93.3 100 N.A. N.A.
Percent
Protein Identity: 73.4 70 N.A. 73.9 66.4 65
Protein Similarity: 87.7 85.5 N.A. 88.4 82.5 81.5
P-Site Identity: 60 60 N.A. 66.6 60 40
P-Site Similarity: 73.3 73.3 N.A. 80 80 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 43 93 0 0 0 0 0 0 8 0 0 93 0 0 % D
% Glu: 0 50 0 0 0 0 0 0 0 0 0 0 8 58 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 93 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 65 0 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 72 8 0 0 15 0 0 0 0 8 15 % K
% Leu: 0 8 8 0 0 0 0 0 8 93 0 86 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 8 0 0 0 0 0 15 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 15 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 86 0 0 8 0 0 0 0 0 8 % R
% Ser: 8 0 0 0 8 0 8 0 58 0 8 0 0 8 36 % S
% Thr: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 65 0 0 29 0 0 79 0 0 0 0 0 0 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 86 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _