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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDYL All Species: 26.36
Human Site: S505 Identified Species: 64.44
UniProt: Q9Y232 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y232 NP_001137443.1 598 66482 S505 S A N E M L L S G R K L T A Q
Chimpanzee Pan troglodytes XP_518216 598 66387 S505 S A N E M L L S G R K L T A Q
Rhesus Macaque Macaca mulatta XP_001119034 674 74908 S581 S A N E M L L S G R K L T A Q
Dog Lupus familis XP_848773 587 65254 S494 S A N E M L L S G R K L T A Q
Cat Felis silvestris
Mouse Mus musculus Q9WTK2 593 65193 S500 S A N E M L F S G R K L T A Q
Rat Rattus norvegicus Q6AYK9 589 65012 S496 S A N E M L L S G R K L T A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507630 676 75369 S583 S A N E M W F S G R K L T A Q
Chicken Gallus gallus XP_418964 544 61077 V466 E A C A K G L V S Q V F W P G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0PJR5 289 31421 R211 S A V F S E E R L E D E T L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781347 617 67230 A525 V A G E M L Y A G R K L T A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 82.7 89.8 N.A. 85.2 84.2 N.A. 75 81.7 N.A. 20.2 N.A. N.A. N.A. N.A. 27.7
Protein Similarity: 100 99.3 85.1 92.3 N.A. 89.3 88.2 N.A. 81.6 86.9 N.A. 29.4 N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 86.6 13.3 N.A. 20 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 86.6 20 N.A. 20 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 10 0 0 0 10 0 0 0 0 0 80 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 10 0 0 80 0 10 10 0 0 10 0 10 0 0 0 % E
% Phe: 0 0 0 10 0 0 20 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 10 0 0 10 0 0 80 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 80 0 0 0 0 % K
% Leu: 0 0 0 0 0 70 60 0 10 0 0 80 0 10 10 % L
% Met: 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 70 % Q
% Arg: 0 0 0 0 0 0 0 10 0 80 0 0 0 0 0 % R
% Ser: 80 0 0 0 10 0 0 70 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 90 0 0 % T
% Val: 10 0 10 0 0 0 0 10 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _