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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE10A
All Species:
3.33
Human Site:
S8
Identified Species:
6.11
UniProt:
Q9Y233
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y233
NP_001124162.1
779
88412
S8
M
R
I
E
E
R
K
S
Q
H
L
T
G
L
T
Chimpanzee
Pan troglodytes
XP_518849
940
103297
C169
C
F
R
R
L
T
E
C
F
L
S
P
S
L
T
Rhesus Macaque
Macaca mulatta
XP_001105004
806
91361
F35
C
K
V
N
F
I
L
F
N
S
F
T
G
L
T
Dog
Lupus familis
XP_541190
794
89954
K18
I
V
P
K
S
A
K
K
G
V
G
G
G
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CA95
790
89389
S12
S
T
E
G
T
V
G
S
C
N
A
T
G
L
T
Rat
Rattus norvegicus
Q9QYJ6
794
90143
C18
C
F
R
R
L
T
E
C
F
L
S
P
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506107
745
84517
L8
M
E
G
S
T
D
Q
L
G
S
G
C
L
T
D
Chicken
Gallus gallus
P52731
862
99990
L13
K
D
A
V
E
K
Y
L
E
N
N
P
Q
F
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957396
843
95237
F18
F
R
R
F
T
D
C
F
L
G
S
S
L
T
D
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
S13
M
V
F
S
D
V
E
S
F
L
D
S
H
P
E
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
H188
H
Q
A
N
S
P
Q
H
H
R
P
Y
D
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
XP_789134
701
80204
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
95
94.3
N.A.
93.1
92.9
N.A.
89.2
23.2
N.A.
77.4
27.8
20
N.A.
35.1
38.9
Protein Similarity:
100
82.6
96
95.8
N.A.
95.9
95.7
N.A.
92
41.5
N.A.
84.8
49
32.6
N.A.
54.6
58.7
P-Site Identity:
100
13.3
26.6
26.6
N.A.
33.3
13.3
N.A.
6.6
6.6
N.A.
6.6
13.3
0
N.A.
0
0
P-Site Similarity:
100
20
40
40
N.A.
40
20
N.A.
13.3
26.6
N.A.
13.3
33.3
13.3
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
0
0
0
0
8
0
0
0
8
% A
% Cys:
24
0
0
0
0
0
8
16
8
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
8
16
0
0
0
0
8
0
8
0
16
% D
% Glu:
0
8
8
8
16
0
24
0
8
0
0
0
0
0
16
% E
% Phe:
8
16
8
8
8
0
0
16
24
0
8
0
0
8
0
% F
% Gly:
0
0
8
8
0
0
8
0
16
8
16
8
31
0
0
% G
% His:
8
0
0
0
0
0
0
8
8
8
0
0
8
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
8
0
8
16
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
8
16
8
24
8
0
16
47
0
% L
% Met:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
0
0
8
16
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
8
24
0
16
0
% P
% Gln:
0
8
0
0
0
0
16
0
8
0
0
0
8
0
0
% Q
% Arg:
0
16
24
16
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
16
16
0
0
24
0
16
24
16
16
0
0
% S
% Thr:
0
8
0
0
24
16
0
0
0
0
0
24
0
16
47
% T
% Val:
0
16
8
8
0
16
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _