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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE10A
All Species:
5.45
Human Site:
T536
Identified Species:
10
UniProt:
Q9Y233
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y233
NP_001124162.1
779
88412
T536
A
I
L
Q
N
N
H
T
L
F
T
D
L
E
R
Chimpanzee
Pan troglodytes
XP_518849
940
103297
T697
A
I
L
Q
N
N
H
T
L
F
T
D
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001105004
806
91361
A563
A
I
L
Q
N
N
H
A
L
F
T
D
L
E
R
Dog
Lupus familis
XP_541190
794
89954
G546
A
I
L
Q
N
N
H
G
L
F
T
D
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CA95
790
89389
G540
A
I
L
Q
N
N
N
G
L
F
T
D
L
E
R
Rat
Rattus norvegicus
Q9QYJ6
794
90143
G546
A
I
L
Q
N
N
N
G
L
F
T
D
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506107
745
84517
H524
K
H
A
V
T
V
A
H
C
M
Y
A
I
L
Q
Chicken
Gallus gallus
P52731
862
99990
I583
T
L
L
M
T
G
R
I
K
K
Y
Y
T
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957396
843
95237
G546
A
I
L
Q
K
T
T
G
I
F
T
E
L
E
R
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
F639
A
M
L
T
T
A
G
F
Q
E
T
L
T
D
V
Fruit Fly
Dros. melanogaster
Q9VJ79
1451
160911
W881
A
I
L
T
T
T
Q
W
W
K
I
F
G
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91119
710
81117
A496
H
G
W
S
V
A
H
A
M
F
A
T
L
M
N
Sea Urchin
Strong. purpuratus
XP_789134
701
80204
T488
D
M
D
H
R
G
L
T
N
S
F
H
A
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
95
94.3
N.A.
93.1
92.9
N.A.
89.2
23.2
N.A.
77.4
27.8
20
N.A.
35.1
38.9
Protein Similarity:
100
82.6
96
95.8
N.A.
95.9
95.7
N.A.
92
41.5
N.A.
84.8
49
32.6
N.A.
54.6
58.7
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
0
6.6
N.A.
60
20
26.6
N.A.
20
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
20
N.A.
73.3
33.3
26.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
8
0
0
16
8
16
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
0
47
0
16
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
8
0
62
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
62
8
8
0
0
8
% F
% Gly:
0
8
0
0
0
16
8
31
0
0
0
0
8
0
0
% G
% His:
8
8
0
8
0
0
39
8
0
0
0
8
0
0
0
% H
% Ile:
0
62
0
0
0
0
0
8
8
0
8
0
8
0
8
% I
% Lys:
8
0
0
0
8
0
0
0
8
16
0
0
0
8
0
% K
% Leu:
0
8
77
0
0
0
8
0
47
0
0
8
62
8
8
% L
% Met:
0
16
0
8
0
0
0
0
8
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
47
47
16
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
54
0
0
8
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
54
% R
% Ser:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
8
0
0
16
31
16
8
24
0
0
62
8
16
0
0
% T
% Val:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _