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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN4
All Species:
20.3
Human Site:
S19
Identified Species:
37.22
UniProt:
Q9Y237
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y237
NP_006214.2
131
13810
S19
A
G
K
G
G
A
A
S
G
S
D
S
A
D
K
Chimpanzee
Pan troglodytes
XP_001161176
130
13821
S19
A
G
K
G
G
A
A
S
G
S
D
S
A
D
K
Rhesus Macaque
Macaca mulatta
XP_001092957
164
17481
S52
A
G
K
G
G
A
A
S
G
S
D
S
A
D
K
Dog
Lupus familis
XP_849005
131
14135
S19
R
G
K
G
G
A
A
S
R
S
D
S
S
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWW6
131
13796
S19
G
G
K
G
G
A
A
S
G
S
D
S
A
D
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420136
125
13164
E19
G
K
G
G
E
S
G
E
G
K
A
Q
G
P
K
Frog
Xenopus laevis
NP_001084775
127
13508
E19
K
G
G
A
A
S
G
E
A
A
D
K
K
A
Q
Zebra Danio
Brachydanio rerio
Q503Y7
128
13645
S19
K
G
A
A
A
S
G
S
G
D
S
D
K
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651364
130
13892
E23
G
G
K
K
P
A
A
E
D
K
S
A
G
K
E
Honey Bee
Apis mellifera
XP_001120560
113
12319
V22
N
A
I
K
S
I
K
V
R
H
I
L
C
E
K
Nematode Worm
Caenorhab. elegans
NP_496824
126
13302
G19
S
G
S
G
K
D
D
G
G
G
Q
K
K
E
A
Sea Urchin
Strong. purpuratus
XP_790053
113
12217
T19
Q
K
K
G
G
T
S
T
V
K
V
R
H
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYY4
130
13640
A20
G
S
K
G
G
K
D
A
G
N
K
D
A
G
K
Conservation
Percent
Protein Identity:
100
94.6
79.2
90
N.A.
96.9
N.A.
N.A.
N.A.
84.7
87
83.2
N.A.
72.5
61.8
71.7
64.1
Protein Similarity:
100
95.4
79.8
93.8
N.A.
98.4
N.A.
N.A.
N.A.
90.8
92.3
89.3
N.A.
82.4
73.2
80.1
72.5
P-Site Identity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
N.A.
20
13.3
20
N.A.
26.6
6.6
20
20
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
N.A.
26.6
33.3
33.3
N.A.
40
13.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
50.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
62.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
8
16
16
47
47
8
8
8
8
8
39
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
16
0
8
8
47
16
0
39
0
% D
% Glu:
0
0
0
0
8
0
0
24
0
0
0
0
0
16
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
31
70
16
70
54
0
24
8
62
8
0
0
16
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
8
0
0
8
0
% I
% Lys:
16
16
62
16
8
8
8
0
0
24
8
16
24
16
62
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% R
% Ser:
8
8
8
0
8
24
8
47
0
39
16
39
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _