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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN4
All Species:
31.82
Human Site:
S60
Identified Species:
58.33
UniProt:
Q9Y237
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y237
NP_006214.2
131
13810
S60
E
A
M
E
K
L
K
S
G
M
R
F
N
E
V
Chimpanzee
Pan troglodytes
XP_001161176
130
13821
S60
E
A
M
E
K
L
K
S
G
M
R
F
N
E
V
Rhesus Macaque
Macaca mulatta
XP_001092957
164
17481
S93
E
A
M
E
K
L
K
S
G
M
R
F
N
E
V
Dog
Lupus familis
XP_849005
131
14135
S60
E
A
M
E
K
L
K
S
G
M
R
F
N
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWW6
131
13796
S60
E
A
M
E
K
L
K
S
G
M
R
F
S
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420136
125
13164
A54
E
A
M
E
K
L
K
A
G
V
R
F
S
E
V
Frog
Xenopus laevis
NP_001084775
127
13508
S56
E
A
M
E
K
L
K
S
G
V
R
F
S
E
V
Zebra Danio
Brachydanio rerio
Q503Y7
128
13645
S57
E
A
M
E
K
I
K
S
G
M
R
F
S
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651364
130
13892
A59
E
A
M
E
K
L
K
A
G
Q
K
F
P
E
V
Honey Bee
Apis mellifera
XP_001120560
113
12319
A42
E
A
L
E
K
L
K
A
G
G
K
F
N
E
V
Nematode Worm
Caenorhab. elegans
NP_496824
126
13302
S55
E
A
I
E
K
L
K
S
G
M
K
F
N
E
V
Sea Urchin
Strong. purpuratus
XP_790053
113
12217
A42
E
A
L
E
K
I
K
A
G
E
R
F
N
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYY4
130
13640
D61
E
A
L
A
K
I
R
D
G
A
D
F
G
A
V
Conservation
Percent
Protein Identity:
100
94.6
79.2
90
N.A.
96.9
N.A.
N.A.
N.A.
84.7
87
83.2
N.A.
72.5
61.8
71.7
64.1
Protein Similarity:
100
95.4
79.8
93.8
N.A.
98.4
N.A.
N.A.
N.A.
90.8
92.3
89.3
N.A.
82.4
73.2
80.1
72.5
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
80
86.6
86.6
N.A.
73.3
73.3
86.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
86.6
93.3
100
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
50.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
62.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
100
0
8
0
0
0
31
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
100
0
0
93
0
0
0
0
0
8
0
0
0
85
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
100
0
93
0
0
0
24
0
0
0
0
% K
% Leu:
0
0
24
0
0
77
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
70
0
0
0
0
0
0
54
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
70
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
62
0
0
0
0
31
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _