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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN4
All Species:
47.88
Human Site:
Y122
Identified Species:
87.78
UniProt:
Q9Y237
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y237
NP_006214.2
131
13810
Y122
P
V
K
T
K
F
G
Y
H
I
I
M
V
E
G
Chimpanzee
Pan troglodytes
XP_001161176
130
13821
Y122
A
V
K
T
K
F
G
Y
H
I
M
V
E
G
R
Rhesus Macaque
Macaca mulatta
XP_001092957
164
17481
Y155
P
V
K
T
K
F
G
Y
H
I
I
M
V
E
G
Dog
Lupus familis
XP_849005
131
14135
Y122
P
I
R
T
E
F
G
Y
R
I
I
M
V
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWW6
131
13796
Y122
P
V
K
T
K
F
G
Y
H
I
I
M
V
E
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420136
125
13164
Y116
P
V
K
T
K
F
G
Y
H
I
I
M
V
E
G
Frog
Xenopus laevis
NP_001084775
127
13508
Y118
P
V
K
T
K
F
G
Y
H
I
I
M
V
E
G
Zebra Danio
Brachydanio rerio
Q503Y7
128
13645
Y119
P
V
K
T
K
F
G
Y
H
I
I
M
V
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651364
130
13892
Y121
P
I
K
T
K
F
G
Y
H
I
I
M
V
E
G
Honey Bee
Apis mellifera
XP_001120560
113
12319
Y104
P
I
K
T
K
F
G
Y
H
I
I
M
V
E
S
Nematode Worm
Caenorhab. elegans
NP_496824
126
13302
Y117
P
V
K
T
K
F
G
Y
H
V
I
M
V
E
G
Sea Urchin
Strong. purpuratus
XP_790053
113
12217
Y104
P
V
K
T
K
H
G
Y
H
I
I
M
I
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYY4
130
13640
I123
K
T
Q
F
G
Y
H
I
I
M
V
E
G
K
K
Conservation
Percent
Protein Identity:
100
94.6
79.2
90
N.A.
96.9
N.A.
N.A.
N.A.
84.7
87
83.2
N.A.
72.5
61.8
71.7
64.1
Protein Similarity:
100
95.4
79.8
93.8
N.A.
98.4
N.A.
N.A.
N.A.
90.8
92.3
89.3
N.A.
82.4
73.2
80.1
72.5
P-Site Identity:
100
60
100
73.3
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
93.3
86.6
93.3
86.6
P-Site Similarity:
100
73.3
100
93.3
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
100
93.3
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
50.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
62.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
8
8
85
0
% E
% Phe:
0
0
0
8
0
85
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
93
0
0
0
0
0
8
8
77
% G
% His:
0
0
0
0
0
8
8
0
85
0
0
0
0
0
0
% H
% Ile:
0
24
0
0
0
0
0
8
8
85
85
0
8
0
0
% I
% Lys:
8
0
85
0
85
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
85
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
85
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
8
0
93
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
70
0
0
0
0
0
0
0
8
8
8
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _