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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIGD1A
All Species:
23.94
Human Site:
Y12
Identified Species:
52.67
UniProt:
Q9Y241
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y241
NP_001093138.1
93
10143
Y12
T
G
V
S
L
P
S
Y
E
E
D
Q
G
S
K
Chimpanzee
Pan troglodytes
XP_001138606
87
9467
Y12
T
G
V
S
L
P
S
Y
E
E
Y
Q
G
S
K
Rhesus Macaque
Macaca mulatta
XP_001115209
93
10170
Y12
T
G
V
S
L
P
S
Y
E
E
D
Q
G
S
K
Dog
Lupus familis
XP_534235
93
10132
Y12
T
D
V
S
L
S
S
Y
D
E
D
Q
G
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLR9
95
10407
Y12
T
D
L
S
L
S
S
Y
D
E
G
Q
G
S
K
Rat
Rattus norvegicus
Q8VH49
93
10283
Y12
T
D
L
S
L
S
S
Y
D
E
G
Q
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513449
95
10473
S14
V
A
L
S
S
Y
Q
S
D
E
D
Q
G
S
K
Chicken
Gallus gallus
NP_001026128
95
10640
T14
P
V
Y
P
E
Y
E
T
E
T
S
Q
T
S
K
Frog
Xenopus laevis
NP_001086336
95
10325
M13
D
V
L
P
T
Y
E
M
A
D
S
Q
T
S
K
Zebra Danio
Brachydanio rerio
NP_956394
99
11142
R15
D
N
E
S
K
L
M
R
K
I
K
Q
N
P
F
Tiger Blowfish
Takifugu rubipres
NP_001072104
87
9794
L12
E
E
N
E
S
K
F
L
R
K
A
K
E
N
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
95.6
89.2
N.A.
85.2
84.9
N.A.
81
67.3
71.5
62.6
65.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
100
96.7
N.A.
92.6
93.5
N.A.
89.4
76.8
85.2
75.7
81.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
66.6
66.6
N.A.
46.6
26.6
20
13.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
80
80
N.A.
60
26.6
33.3
20
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
28
0
0
0
0
0
0
37
10
37
0
0
0
0
% D
% Glu:
10
10
10
10
10
0
19
0
37
64
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
28
0
0
0
0
0
0
0
0
19
0
64
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
10
10
10
10
0
0
82
% K
% Leu:
0
0
37
0
55
10
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
10
0
0
19
0
28
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
91
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
73
19
28
55
10
0
0
19
0
0
82
0
% S
% Thr:
55
0
0
0
10
0
0
10
0
10
0
0
19
0
0
% T
% Val:
10
19
37
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
28
0
55
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _