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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF19
All Species:
12.42
Human Site:
S278
Identified Species:
34.17
UniProt:
Q9Y242
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y242
NP_001070979.1
345
37184
S278
R
P
R
K
Y
P
V
S
A
P
M
A
P
P
A
Chimpanzee
Pan troglodytes
Q7YR48
345
37126
S278
R
P
R
K
Y
P
V
S
A
P
V
A
P
P
A
Rhesus Macaque
Macaca mulatta
Q5TM48
345
37055
S278
R
P
R
K
Y
P
V
S
A
P
M
A
P
P
A
Dog
Lupus familis
XP_532065
344
37180
S277
C
P
W
K
H
P
V
S
T
P
R
A
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99KJ5
263
28049
R219
V
S
P
A
P
P
T
R
N
R
R
K
S
A
H
Rat
Rattus norvegicus
NP_998726
264
28372
R220
P
A
P
P
T
R
N
R
R
K
S
A
H
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520149
156
16624
G111
A
P
A
C
G
A
G
G
A
R
A
Q
G
A
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686736
516
56794
P420
R
P
R
K
H
P
L
P
Q
P
S
L
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792745
553
59758
N494
D
V
T
Q
T
E
Y
N
S
L
P
C
A
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96.2
85.2
N.A.
61.7
63.1
N.A.
28.7
N.A.
N.A.
27.9
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
99.4
97.6
88.6
N.A.
66.9
67.5
N.A.
33.9
N.A.
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
33
P-Site Identity:
100
93.3
100
66.6
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
12
0
12
0
0
45
0
12
56
12
23
45
% A
% Cys:
12
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
12
12
0
0
0
0
12
0
12
% G
% His:
0
0
0
0
23
0
0
0
0
0
0
0
12
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
56
0
0
0
0
0
12
0
12
0
12
0
% K
% Leu:
0
0
0
0
0
0
12
0
0
12
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
12
12
0
0
0
0
0
0
% N
% Pro:
12
67
23
12
12
67
0
12
0
56
12
0
56
45
23
% P
% Gln:
0
0
0
12
0
0
0
0
12
0
0
12
0
0
0
% Q
% Arg:
45
0
45
0
0
12
0
23
12
23
23
0
0
0
0
% R
% Ser:
0
12
0
0
0
0
0
45
12
0
23
0
12
23
0
% S
% Thr:
0
0
12
0
23
0
12
0
12
0
0
0
0
0
0
% T
% Val:
12
12
0
0
0
0
45
0
0
0
12
0
0
0
12
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _