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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AKT3 All Species: 25.45
Human Site: Y414 Identified Species: 46.67
UniProt: Q9Y243 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y243 NP_005456.1 479 55775 Y414 G V N W Q D V Y D K K L V P P
Chimpanzee Pan troglodytes XP_512662 481 55720 V418 S I N W Q D V V Q K K L L P P
Rhesus Macaque Macaca mulatta XP_001104624 604 69574 Y539 G V N W Q D V Y D K K L V P P
Dog Lupus familis XP_547496 479 55710 Y414 G V N W Q D V Y D K K L V P P
Cat Felis silvestris
Mouse Mus musculus Q9WUA6 479 55696 Y414 G V N W Q D V Y D K K L V P P
Rat Rattus norvegicus Q63484 479 55778 Y414 G V N W Q D V Y D K K L V P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513899 512 59226 W452 S F F V G L N W Q D V Y D K K
Chicken Gallus gallus Q6U1I9 432 48872 F373 N K K I T P P F N P N V S G P
Frog Xenopus laevis Q98TY9 481 56023 Y418 G I V W Q D V Y E K K L V P P
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 F374 A K K L T P P F N P N V T G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 V532 S I N W T D L V L K K I P P P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17941 541 62181 Y459 T V D W E A T Y R K E I E P P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P87253 1142 127954 W1081 P F F R N I N W D D I Y H K R
Conservation
Percent
Protein Identity: 100 77.7 78.6 99.5 N.A. 99.5 99.1 N.A. 86.1 40.2 82.9 41.5 N.A. 51.3 N.A. 51.9 N.A.
Protein Similarity: 100 88.7 79.1 100 N.A. 99.7 99.3 N.A. 87.3 55.3 90.8 56.7 N.A. 62.6 N.A. 67.6 N.A.
P-Site Identity: 100 66.6 100 100 N.A. 100 100 N.A. 0 6.6 80 6.6 N.A. 46.6 N.A. 40 N.A.
P-Site Similarity: 100 80 100 100 N.A. 100 100 N.A. 6.6 26.6 93.3 26.6 N.A. 66.6 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 21
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 30
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 62 0 0 47 16 0 0 8 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 8 0 8 0 8 0 0 % E
% Phe: 0 16 16 0 0 0 0 16 0 0 0 0 0 0 0 % F
% Gly: 47 0 0 0 8 0 0 0 0 0 0 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 24 0 8 0 8 0 0 0 0 8 16 0 0 0 % I
% Lys: 0 16 16 0 0 0 0 0 0 70 62 0 0 16 8 % K
% Leu: 0 0 0 8 0 8 8 0 8 0 0 54 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 54 0 8 0 16 0 16 0 16 0 0 0 0 % N
% Pro: 8 0 0 0 0 16 16 0 0 16 0 0 8 70 85 % P
% Gln: 0 0 0 0 54 0 0 0 16 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 8 % R
% Ser: 24 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 8 0 0 0 24 0 8 0 0 0 0 0 8 0 0 % T
% Val: 0 47 8 8 0 0 54 16 0 0 8 16 47 0 0 % V
% Trp: 0 0 0 70 0 0 0 16 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _