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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM50B All Species: 36.36
Human Site: S121 Identified Species: 72.73
UniProt: Q9Y247 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y247 NP_036267.1 325 38709 S121 K R K I S C L S F A L D D L D
Chimpanzee Pan troglodytes XP_001146118 452 50373 S234 K R K I S S L S F T L E E E E
Rhesus Macaque Macaca mulatta XP_001093508 325 38467 S121 K R K I S S L S F T L E E E E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WTJ8 334 39575 S121 K R K I S N L S F T L D E E E
Rat Rattus norvegicus NP_001100819 335 39649 S121 K R K I S N L S F T L D E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518058 312 37095 S84 K R K I S S L S F T L D E E E
Chicken Gallus gallus
Frog Xenopus laevis Q2VPH1 340 40315 S121 K R K I A S L S F N L E E D E
Zebra Danio Brachydanio rerio Q568K9 341 40523 S121 K R K I A S L S F N P D E G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAY7 359 42838 S120 K R Q I Q A L S F N L D D D E
Honey Bee Apis mellifera XP_624083 345 40901 S120 K K Q I Q A L S F N L Y E D E
Nematode Worm Caenorhab. elegans Q18691 326 37886 S118 H T Q K R F L S F A F D D E E
Sea Urchin Strong. purpuratus XP_001183761 318 37639 S113 L K N A G T L S F N M D E D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.4 78.1 N.A. N.A. 83.8 83.8 N.A. 55.6 N.A. 71.7 70 N.A. 54.5 53.6 44.1 58.4
Protein Similarity: 100 66.1 91.6 N.A. N.A. 93.1 92.2 N.A. 69.2 N.A. 87.3 85.9 N.A. 74.9 77.3 66.2 81.5
P-Site Identity: 100 60 60 N.A. N.A. 66.6 66.6 N.A. 66.6 N.A. 53.3 53.3 N.A. 60 40 40 26.6
P-Site Similarity: 100 80 80 N.A. N.A. 80 80 N.A. 80 N.A. 80 73.3 N.A. 73.3 66.6 53.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 17 17 0 0 0 17 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 67 25 34 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 25 75 50 92 % E
% Phe: 0 0 0 0 0 9 0 0 100 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 84 17 67 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 100 0 0 0 75 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 9 0 0 17 0 0 0 42 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 0 25 0 17 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 75 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 50 42 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 9 0 0 0 9 0 0 0 42 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _