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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS2 All Species: 45.15
Human Site: S131 Identified Species: 58.43
UniProt: Q9Y248 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y248 NP_057179.1 185 21428 S131 R I A K L R V S A D S F V R Q
Chimpanzee Pan troglodytes XP_511151 185 21423 S131 R I A K L R V S A D S F V R Q
Rhesus Macaque Macaca mulatta XP_001082775 185 21369 S131 R I A K L R V S A D S F V R Q
Dog Lupus familis XP_851786 185 21303 S131 R I A K L R V S A D S F V R Q
Cat Felis silvestris
Mouse Mus musculus Q9D600 185 21218 S131 R M A K L R V S A D S F V R Q
Rat Rattus norvegicus NP_001099660 185 21245 S131 R M A K L R V S A D S F V R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511142 163 18886 S109 R I A K L R L S A D S F V R Q
Chicken Gallus gallus XP_414187 150 17099 S96 R M A K L R L S A D S F V R Q
Frog Xenopus laevis Q7ZT46 185 21306 S131 R I A K L R L S A D S F V K G
Zebra Danio Brachydanio rerio NP_001019610 182 21133 L128 W D T R M A K L R L S A D S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQY9 203 23095 S131 R E S K L R T S I D A F I K G
Honey Bee Apis mellifera XP_392289 186 21170 S131 R M S K L R T S I D A F L K S
Nematode Worm Caenorhab. elegans O62193 180 20303 D106 L V R D A R E D I F E V E A V
Sea Urchin Strong. purpuratus XP_790204 124 14307 I71 M A K L R Q S I D K F V K D Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147013 211 24311 G142 R F H K V E T G L E T I S G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7A8 210 24272 N142 R L H K L E T N L G S F Q G T
Baker's Yeast Sacchar. cerevisiae P40359 213 25042 V156 R E I R Q I K V L K G L K Y L
Red Bread Mold Neurospora crassa Q7SAA9 273 29811 S199 R A A K M R S S T S A L E G F
Conservation
Percent
Protein Identity: 100 99.4 98.9 94.5 N.A. 92.4 92.9 N.A. 77.8 63.7 85.9 78.9 N.A. 40.8 51 36.2 40
Protein Similarity: 100 100 99.4 98.9 N.A. 97.8 97.8 N.A. 84.3 70.2 93.5 92.4 N.A. 68.9 72.5 64.3 52.4
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 86.6 80 6.6 N.A. 46.6 46.6 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 20 N.A. 73.3 80 13.3 13.3
Percent
Protein Identity: N.A. 34.6 N.A. 36.6 25.3 24.5
Protein Similarity: N.A. 56.4 N.A. 56.1 49.7 40.2
P-Site Identity: N.A. 13.3 N.A. 33.3 6.6 33.3
P-Site Similarity: N.A. 40 N.A. 46.6 13.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 56 0 6 6 0 0 50 0 17 6 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 6 0 0 0 6 6 62 0 0 6 6 0 % D
% Glu: 0 12 0 0 0 12 6 0 0 6 6 0 12 0 0 % E
% Phe: 0 6 0 0 0 0 0 0 0 6 6 67 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 6 0 6 6 0 0 17 12 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 6 0 0 6 0 6 17 0 0 6 6 0 0 % I
% Lys: 0 0 6 78 0 0 12 0 0 12 0 0 12 17 0 % K
% Leu: 6 6 0 6 67 0 17 6 17 6 0 12 6 0 6 % L
% Met: 6 23 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 6 6 0 0 0 0 0 0 6 0 50 % Q
% Arg: 84 0 6 12 6 73 0 0 6 0 0 0 0 45 6 % R
% Ser: 0 0 12 0 0 0 12 67 0 6 62 0 6 6 6 % S
% Thr: 0 0 6 0 0 0 23 0 6 0 6 0 0 0 6 % T
% Val: 0 6 0 0 6 0 34 6 0 0 0 12 50 0 6 % V
% Trp: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _