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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS2 All Species: 36.67
Human Site: T83 Identified Species: 47.45
UniProt: Q9Y248 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.12
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y248 NP_057179.1 185 21428 T83 D H E R K E E T F T P M P S P
Chimpanzee Pan troglodytes XP_511151 185 21423 T83 D H E R K E E T F T P M P S P
Rhesus Macaque Macaca mulatta XP_001082775 185 21369 T83 D H E R K E E T F T P M P S P
Dog Lupus familis XP_851786 185 21303 T83 D H E R K E E T F T P M P S P
Cat Felis silvestris
Mouse Mus musculus Q9D600 185 21218 T83 D E E R K E E T F T P V P S P
Rat Rattus norvegicus NP_001099660 185 21245 T83 D E E R K E E T F T P V P S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511142 163 18886 T61 D K E R K E D T F T P M P N P
Chicken Gallus gallus XP_414187 150 17099 T48 D Q E R K E D T F T P M P S P
Frog Xenopus laevis Q7ZT46 185 21306 T83 D Q E R R E E T F T P M P S P
Zebra Danio Brachydanio rerio NP_001019610 182 21133 K80 D I R E Q E R K L D T F T P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQY9 203 23095 F83 E E E K R S K F F T K M P C E
Honey Bee Apis mellifera XP_392289 186 21170 L83 E E E K L S K L F T K M P S N
Nematode Worm Caenorhab. elegans O62193 180 20303 N58 I L M K R K H N C K V V A P Q
Sea Urchin Strong. purpuratus XP_790204 124 14307 F23 Q E H D S A V F Q P M V N P H
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147013 211 24311 R94 E A E R E S P R E F Q P L P F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7A8 210 24272 S94 E A E R E S Q S T F Q A L P F
Baker's Yeast Sacchar. cerevisiae P40359 213 25042 H108 K I Q Y E K T H P D R F S E L
Red Bread Mold Neurospora crassa Q7SAA9 273 29811 P151 P S N V A E S P A G Y L P Y H
Conservation
Percent
Protein Identity: 100 99.4 98.9 94.5 N.A. 92.4 92.9 N.A. 77.8 63.7 85.9 78.9 N.A. 40.8 51 36.2 40
Protein Similarity: 100 100 99.4 98.9 N.A. 97.8 97.8 N.A. 84.3 70.2 93.5 92.4 N.A. 68.9 72.5 64.3 52.4
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 80 86.6 86.6 13.3 N.A. 33.3 40 0 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 20 N.A. 60 60 26.6 6.6
Percent
Protein Identity: N.A. 34.6 N.A. 36.6 25.3 24.5
Protein Similarity: N.A. 56.4 N.A. 56.1 49.7 40.2
P-Site Identity: N.A. 13.3 N.A. 13.3 0 13.3
P-Site Similarity: N.A. 26.6 N.A. 40 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 6 6 0 0 6 0 0 6 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 6 0 0 0 0 6 0 % C
% Asp: 56 0 0 6 0 0 12 0 0 12 0 0 0 0 0 % D
% Glu: 23 28 73 6 17 62 39 0 6 0 0 0 0 6 6 % E
% Phe: 0 0 0 0 0 0 0 12 62 12 0 12 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % G
% His: 0 23 6 0 0 0 6 6 0 0 0 0 0 0 12 % H
% Ile: 6 12 0 0 0 0 0 0 0 0 0 0 0 0 6 % I
% Lys: 6 6 0 17 45 12 12 6 0 6 12 0 0 0 0 % K
% Leu: 0 6 0 0 6 0 0 6 6 0 0 6 12 0 6 % L
% Met: 0 0 6 0 0 0 0 0 0 0 6 50 0 0 0 % M
% Asn: 0 0 6 0 0 0 0 6 0 0 0 0 6 6 6 % N
% Pro: 6 0 0 0 0 0 6 6 6 6 50 6 67 28 50 % P
% Gln: 6 12 6 0 6 0 6 0 6 0 12 0 0 0 6 % Q
% Arg: 0 0 6 62 17 0 6 6 0 0 6 0 0 0 0 % R
% Ser: 0 6 0 0 6 23 6 6 0 0 0 0 6 50 0 % S
% Thr: 0 0 0 0 0 0 6 50 6 62 6 0 6 0 0 % T
% Val: 0 0 0 6 0 0 6 0 0 0 6 23 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 0 0 0 6 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _