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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LZTS1
All Species:
23.94
Human Site:
S283
Identified Species:
58.52
UniProt:
Q9Y250
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y250
NP_066300.1
596
66613
S283
A
L
Q
K
L
Q
R
S
F
E
E
K
E
L
A
Chimpanzee
Pan troglodytes
XP_519639
394
43295
K163
K
P
K
E
Q
E
L
K
P
G
L
C
S
G
A
Rhesus Macaque
Macaca mulatta
XP_001101161
596
66547
S283
A
L
Q
K
L
Q
R
S
L
E
E
K
E
L
A
Dog
Lupus familis
XP_543262
605
67492
S283
E
L
Q
K
L
Q
R
S
L
E
E
K
E
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P60853
599
67290
S283
A
L
Q
K
L
Q
R
S
F
D
E
K
E
F
A
Rat
Rattus norvegicus
Q8CFC9
601
67547
S283
A
L
Q
K
L
Q
R
S
F
D
E
K
E
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505720
616
69251
S297
E
L
R
E
L
Q
C
S
L
E
E
K
E
L
A
Chicken
Gallus gallus
XP_428882
604
68145
S290
E
L
Q
E
L
Q
L
S
F
E
E
K
E
A
S
Frog
Xenopus laevis
Q5U4W1
666
76282
V343
N
E
A
A
I
C
Q
V
Y
E
E
K
Q
K
R
Zebra Danio
Brachydanio rerio
Q1LWB0
781
89566
L299
Y
Q
E
E
L
H
R
L
R
T
E
R
D
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.7
98.9
90.2
N.A.
89.6
89.5
N.A.
79.5
74
37.5
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
66.1
99.5
93.3
N.A.
93.3
93.3
N.A.
87.1
83.9
54.9
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
86.6
N.A.
86.6
86.6
N.A.
66.6
66.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
93.3
93.3
N.A.
80
80
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
10
10
0
0
0
0
0
0
0
0
0
10
70
% A
% Cys:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
20
0
0
10
0
0
% D
% Glu:
30
10
10
40
0
10
0
0
0
60
90
0
70
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
0
0
20
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
50
0
0
0
10
0
0
0
80
0
10
0
% K
% Leu:
0
70
0
0
80
0
20
10
30
0
10
0
0
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
10
60
0
10
70
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
60
0
10
0
0
10
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
0
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _