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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLH
All Species:
5.45
Human Site:
S547
Identified Species:
10
UniProt:
Q9Y253
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y253
NP_006493.1
713
78413
S547
K
Q
K
Q
L
N
N
S
S
V
S
S
P
Q
Q
Chimpanzee
Pan troglodytes
XP_518497
713
78354
S547
K
Q
K
Q
L
N
N
S
S
V
S
S
P
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532150
712
78332
P547
K
Q
K
Q
L
N
N
P
S
I
F
F
P
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN0
694
76148
K528
T
G
S
Q
S
F
F
K
Q
K
S
L
L
L
Q
Rat
Rattus norvegicus
NP_001101674
689
75727
K524
T
S
G
S
P
G
T
K
S
F
F
K
Q
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516192
729
78058
F547
D
A
V
R
R
Q
D
F
P
S
G
P
P
P
V
Chicken
Gallus gallus
NP_001001304
673
73621
H508
L
P
A
A
T
H
A
H
S
P
A
A
S
S
M
Frog
Xenopus laevis
NP_001087074
684
75120
S515
T
N
M
P
G
S
P
S
G
S
P
T
E
L
N
Zebra Danio
Brachydanio rerio
NP_001035337
743
82024
D546
N
V
S
L
D
D
E
D
Q
S
V
C
A
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649371
885
99008
E562
S
T
P
A
E
F
K
E
S
F
F
S
Q
Y
L
Honey Bee
Apis mellifera
XP_001122310
429
48500
E264
K
F
G
H
I
V
T
E
S
L
N
C
N
V
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797437
822
90146
H537
A
S
H
S
V
A
S
H
P
S
T
V
A
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568638
672
73967
E506
T
Y
T
L
P
N
F
E
N
Q
D
K
D
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.2
N.A.
79.6
77.6
N.A.
64.4
51.8
53.1
46.7
N.A.
31.2
27.9
N.A.
38.5
Protein Similarity:
100
99.7
N.A.
90.8
N.A.
85.9
85.1
N.A.
73.6
68
67.7
61.5
N.A.
48.4
40.3
N.A.
55.6
P-Site Identity:
100
100
N.A.
66.6
N.A.
20
6.6
N.A.
6.6
6.6
6.6
0
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
100
N.A.
73.3
N.A.
20
13.3
N.A.
20
26.6
20
13.3
N.A.
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
16
0
8
8
0
0
0
8
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
8
0
0
0
8
8
8
8
0
0
8
0
8
0
8
% D
% Glu:
0
0
0
0
8
0
8
24
0
0
0
0
8
0
8
% E
% Phe:
0
8
0
0
0
16
16
8
0
16
24
8
0
0
0
% F
% Gly:
0
8
16
0
8
8
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
8
8
0
8
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
31
0
24
0
0
0
8
16
0
8
0
16
0
8
0
% K
% Leu:
8
0
0
16
24
0
0
0
0
8
0
8
8
16
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
16
% M
% Asn:
8
8
0
0
0
31
24
0
8
0
8
0
8
0
8
% N
% Pro:
0
8
8
8
16
0
8
8
16
8
8
8
31
24
0
% P
% Gln:
0
24
0
31
0
8
0
0
16
8
0
0
16
16
31
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
16
16
8
8
8
24
54
31
24
24
8
16
8
% S
% Thr:
31
8
8
0
8
0
16
0
0
0
8
8
0
0
0
% T
% Val:
0
8
8
0
8
8
0
0
0
16
8
8
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _