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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLH
All Species:
12.73
Human Site:
S610
Identified Species:
23.33
UniProt:
Q9Y253
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y253
NP_006493.1
713
78413
S610
S
M
H
A
S
S
A
S
K
S
V
L
E
V
T
Chimpanzee
Pan troglodytes
XP_518497
713
78354
S610
S
M
H
A
S
S
A
S
K
S
A
L
E
V
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532150
712
78332
S610
S
P
S
R
L
A
S
S
S
S
A
L
E
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN0
694
76148
S591
E
M
N
V
A
G
D
S
P
N
V
L
D
S
P
Rat
Rattus norvegicus
NP_001101674
689
75727
N587
K
A
V
S
T
E
V
N
V
A
G
N
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516192
729
78058
G610
A
S
A
E
S
A
V
G
R
S
G
P
G
Q
R
Chicken
Gallus gallus
NP_001001304
673
73621
S571
T
P
S
T
P
P
S
S
R
I
L
P
K
L
K
Frog
Xenopus laevis
NP_001087074
684
75120
H578
V
L
T
A
T
G
E
H
E
S
C
C
T
T
S
Zebra Danio
Brachydanio rerio
NP_001035337
743
82024
I609
S
D
E
S
P
A
G
I
S
S
F
F
Q
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649371
885
99008
S625
L
T
S
D
T
H
M
S
K
P
E
G
Q
S
S
Honey Bee
Apis mellifera
XP_001122310
429
48500
I327
K
F
P
G
K
Q
A
I
I
S
L
N
M
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797437
822
90146
K600
K
D
R
E
I
Q
D
K
K
S
Q
T
L
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568638
672
73967
N569
S
I
V
D
I
F
K
N
Y
N
A
T
P
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.2
N.A.
79.6
77.6
N.A.
64.4
51.8
53.1
46.7
N.A.
31.2
27.9
N.A.
38.5
Protein Similarity:
100
99.7
N.A.
90.8
N.A.
85.9
85.1
N.A.
73.6
68
67.7
61.5
N.A.
48.4
40.3
N.A.
55.6
P-Site Identity:
100
93.3
N.A.
40
N.A.
26.6
0
N.A.
13.3
6.6
13.3
13.3
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
93.3
N.A.
53.3
N.A.
53.3
26.6
N.A.
33.3
46.6
40
40
N.A.
33.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
24
8
24
24
0
0
8
24
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
16
0
16
0
0
16
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
8
16
0
8
8
0
8
0
8
0
24
0
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
8
0
16
8
8
0
0
16
8
8
0
0
% G
% His:
0
0
16
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
16
0
0
16
8
8
0
0
0
0
0
% I
% Lys:
24
0
0
0
8
0
8
8
31
0
0
0
8
0
24
% K
% Leu:
8
8
0
0
8
0
0
0
0
0
16
31
8
16
16
% L
% Met:
0
24
0
0
0
0
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
8
0
0
0
0
16
0
16
0
16
0
0
0
% N
% Pro:
0
16
8
0
16
8
0
0
8
8
0
16
8
8
8
% P
% Gln:
0
0
0
0
0
16
0
0
0
0
8
0
16
8
0
% Q
% Arg:
0
0
8
8
0
0
0
0
16
0
0
0
0
8
8
% R
% Ser:
39
8
24
16
24
16
16
47
16
62
0
0
8
24
24
% S
% Thr:
8
8
8
8
24
0
0
0
0
0
0
16
8
8
16
% T
% Val:
8
0
16
8
0
0
16
0
8
0
16
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _