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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLH
All Species:
17.27
Human Site:
S668
Identified Species:
31.67
UniProt:
Q9Y253
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y253
NP_006493.1
713
78413
S668
K
S
F
L
Q
P
H
S
S
N
P
Q
V
V
S
Chimpanzee
Pan troglodytes
XP_518497
713
78354
S668
K
S
F
L
Q
P
H
S
S
N
P
Q
V
V
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532150
712
78332
S668
K
S
F
L
Q
P
H
S
S
T
M
Q
V
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN0
694
76148
T649
K
S
F
L
Q
P
C
T
S
K
P
Q
A
I
P
Rat
Rattus norvegicus
NP_001101674
689
75727
T645
K
S
F
L
Q
P
C
T
S
K
P
Q
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516192
729
78058
Y668
E
M
P
E
H
A
D
Y
H
F
A
V
E
L
Q
Chicken
Gallus gallus
NP_001001304
673
73621
V629
H
M
D
Y
H
F
A
V
E
L
Q
R
S
F
Q
Frog
Xenopus laevis
NP_001087074
684
75120
P636
D
S
F
S
A
P
S
P
S
R
A
P
P
V
C
Zebra Danio
Brachydanio rerio
NP_001035337
743
82024
E667
Q
A
V
A
P
A
G
E
R
V
C
S
P
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649371
885
99008
V683
F
D
E
I
E
S
S
V
S
N
Y
K
E
C
Y
Honey Bee
Apis mellifera
XP_001122310
429
48500
S385
S
R
S
Y
T
L
N
S
Y
K
P
K
N
M
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797437
822
90146
D658
P
E
M
S
S
D
E
D
F
E
D
S
R
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568638
672
73967
V627
T
D
E
I
D
Q
S
V
F
D
E
L
P
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.2
N.A.
79.6
77.6
N.A.
64.4
51.8
53.1
46.7
N.A.
31.2
27.9
N.A.
38.5
Protein Similarity:
100
99.7
N.A.
90.8
N.A.
85.9
85.1
N.A.
73.6
68
67.7
61.5
N.A.
48.4
40.3
N.A.
55.6
P-Site Identity:
100
100
N.A.
80
N.A.
60
66.6
N.A.
0
0
33.3
0
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
80
N.A.
73.3
73.3
N.A.
13.3
6.6
33.3
13.3
N.A.
33.3
40
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
16
8
0
0
0
16
0
16
16
0
% A
% Cys:
0
0
0
0
0
0
16
0
0
0
8
0
0
8
8
% C
% Asp:
8
16
8
0
8
8
8
8
0
8
8
0
0
0
0
% D
% Glu:
8
8
16
8
8
0
8
8
8
8
8
0
16
0
16
% E
% Phe:
8
0
47
0
0
8
0
0
16
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
16
0
24
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
39
0
0
0
0
0
0
0
0
24
0
16
0
0
0
% K
% Leu:
0
0
0
39
0
8
0
0
0
8
0
8
0
8
0
% L
% Met:
0
16
8
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
24
0
0
8
0
0
% N
% Pro:
8
0
8
0
8
47
0
8
0
0
39
8
24
0
24
% P
% Gln:
8
0
0
0
39
8
0
0
0
0
8
39
0
0
16
% Q
% Arg:
0
8
0
0
0
0
0
0
8
8
0
8
8
0
0
% R
% Ser:
8
47
8
16
8
8
24
31
54
0
0
16
8
0
24
% S
% Thr:
8
0
0
0
8
0
0
16
0
8
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
24
0
8
0
8
24
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
8
8
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _