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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLH
All Species:
16.67
Human Site:
T184
Identified Species:
30.56
UniProt:
Q9Y253
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y253
NP_006493.1
713
78413
T184
S
L
Q
I
D
N
L
T
S
P
D
L
Q
L
T
Chimpanzee
Pan troglodytes
XP_518497
713
78354
T184
S
L
Q
I
D
N
L
T
S
P
D
L
Q
L
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532150
712
78332
T184
S
L
Q
I
D
N
N
T
S
P
D
L
Q
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN0
694
76148
L177
L
L
Q
W
L
D
S
L
Q
S
D
D
P
T
S
Rat
Rattus norvegicus
NP_001101674
689
75727
S176
G
L
L
Q
W
L
G
S
L
E
K
D
D
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516192
729
78058
S184
S
L
P
F
G
D
S
S
S
P
D
L
R
L
T
Chicken
Gallus gallus
NP_001001304
673
73621
L156
G
L
P
A
E
P
G
L
Q
P
A
D
K
E
E
Frog
Xenopus laevis
NP_001087074
684
75120
S161
G
M
D
R
D
S
L
S
K
E
E
L
R
R
H
Zebra Danio
Brachydanio rerio
NP_001035337
743
82024
S182
L
L
S
S
S
T
E
S
S
P
A
D
L
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649371
885
99008
R199
Q
N
D
L
P
A
V
R
Q
S
D
I
R
L
L
Honey Bee
Apis mellifera
XP_001122310
429
48500
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797437
822
90146
D174
E
T
W
L
T
S
S
D
L
A
T
K
R
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568638
672
73967
L155
E
V
L
K
S
H
I
L
G
M
N
R
E
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.2
N.A.
79.6
77.6
N.A.
64.4
51.8
53.1
46.7
N.A.
31.2
27.9
N.A.
38.5
Protein Similarity:
100
99.7
N.A.
90.8
N.A.
85.9
85.1
N.A.
73.6
68
67.7
61.5
N.A.
48.4
40.3
N.A.
55.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
20
13.3
N.A.
53.3
13.3
20
20
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
33.3
20
N.A.
73.3
26.6
53.3
26.6
N.A.
40
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
8
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
31
16
0
8
0
0
47
31
8
8
0
% D
% Glu:
16
0
0
0
8
0
8
0
0
16
8
0
8
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
0
8
0
16
0
8
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
0
24
0
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
0
8
8
8
0
0
% K
% Leu:
16
62
16
16
8
8
24
24
16
0
0
39
8
47
16
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
24
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
16
0
8
8
0
0
0
47
0
0
8
8
0
% P
% Gln:
8
0
31
8
0
0
0
0
24
0
0
0
24
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
8
31
8
0
% R
% Ser:
31
0
8
8
16
16
24
31
39
16
0
0
0
0
8
% S
% Thr:
0
8
0
0
8
8
0
24
0
0
8
0
0
8
39
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _