KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLH
All Species:
14.24
Human Site:
T438
Identified Species:
26.11
UniProt:
Q9Y253
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y253
NP_006493.1
713
78413
T438
A
S
A
P
S
S
S
T
D
I
T
S
F
L
S
Chimpanzee
Pan troglodytes
XP_518497
713
78354
T438
A
S
A
P
S
S
S
T
D
I
T
S
F
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532150
712
78332
T438
A
P
A
P
S
S
C
T
D
I
T
T
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN0
694
76148
T419
T
E
W
S
P
P
L
T
M
L
F
L
C
A
T
Rat
Rattus norvegicus
NP_001101674
689
75727
S415
S
G
V
Q
T
E
W
S
P
P
L
T
M
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516192
729
78058
A438
A
P
A
P
P
P
G
A
S
I
T
S
F
L
S
Chicken
Gallus gallus
NP_001001304
673
73621
Q399
N
D
A
F
A
L
I
Q
N
C
N
M
A
G
A
Frog
Xenopus laevis
NP_001087074
684
75120
N406
F
V
L
L
K
S
F
N
A
A
G
M
H
Q
A
Zebra Danio
Brachydanio rerio
NP_001035337
743
82024
S437
S
D
A
P
S
S
S
S
A
G
I
T
G
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649371
885
99008
S453
G
K
F
E
T
V
S
S
G
Q
N
K
L
Q
E
Honey Bee
Apis mellifera
XP_001122310
429
48500
I155
F
V
V
G
Y
S
E
I
G
K
N
D
E
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797437
822
90146
L428
V
E
G
G
S
S
K
L
G
S
I
Q
S
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568638
672
73967
A397
V
T
K
I
Q
E
D
A
F
N
L
F
Q
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.2
N.A.
79.6
77.6
N.A.
64.4
51.8
53.1
46.7
N.A.
31.2
27.9
N.A.
38.5
Protein Similarity:
100
99.7
N.A.
90.8
N.A.
85.9
85.1
N.A.
73.6
68
67.7
61.5
N.A.
48.4
40.3
N.A.
55.6
P-Site Identity:
100
100
N.A.
80
N.A.
6.6
6.6
N.A.
60
6.6
6.6
33.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
86.6
N.A.
20
33.3
N.A.
60
26.6
13.3
53.3
N.A.
20
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
47
0
8
0
0
16
16
8
0
0
8
16
24
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% C
% Asp:
0
16
0
0
0
0
8
0
24
0
0
8
0
0
0
% D
% Glu:
0
16
0
8
0
16
8
0
0
0
0
0
8
8
16
% E
% Phe:
16
0
8
8
0
0
8
0
8
0
8
8
31
16
8
% F
% Gly:
8
8
8
16
0
0
8
0
24
8
8
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
31
16
0
0
0
0
% I
% Lys:
0
8
8
0
8
0
8
0
0
8
0
8
0
0
0
% K
% Leu:
0
0
8
8
0
8
8
8
0
8
16
8
8
39
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
16
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
8
8
24
0
0
0
0
% N
% Pro:
0
16
0
39
16
16
0
0
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
8
0
8
0
8
8
16
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
16
0
8
39
54
31
24
8
8
0
24
8
0
31
% S
% Thr:
8
8
0
0
16
0
0
31
0
0
31
24
0
0
8
% T
% Val:
16
16
16
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _