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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK6
All Species:
9.7
Human Site:
S278
Identified Species:
19.39
UniProt:
Q9Y257
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y257
NP_004814.1
313
33747
S278
L
P
P
P
C
P
A
S
F
N
A
D
E
D
D
Chimpanzee
Pan troglodytes
XP_524250
313
33801
S278
L
P
P
P
C
P
A
S
F
N
E
D
E
D
D
Rhesus Macaque
Macaca mulatta
XP_001106822
314
34300
S279
L
P
P
P
C
P
A
S
F
N
E
D
E
D
D
Dog
Lupus familis
XP_541645
313
34104
G278
L
P
S
P
C
P
A
G
S
R
E
D
E
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O08581
336
38257
D289
V
K
K
D
K
D
E
D
L
V
H
I
M
E
H
Rat
Rattus norvegicus
Q9Z2T2
336
38210
D289
V
K
K
D
K
D
E
D
Q
V
H
I
M
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516092
322
34925
A289
L
V
L
P
P
A
A
A
E
E
E
E
E
D
D
Chicken
Gallus gallus
XP_419561
336
38076
D289
V
K
K
D
K
E
E
D
H
V
H
I
M
E
H
Frog
Xenopus laevis
Q63ZI0
374
42700
S263
R
D
A
E
E
R
A
S
L
A
G
N
R
N
S
Zebra Danio
Brachydanio rerio
NP_001025245
315
35059
E276
L
P
S
C
E
E
D
E
E
D
K
E
P
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
L262
R
D
E
Q
E
A
I
L
A
A
Q
G
L
V
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL25
443
49308
A377
S
I
S
Q
F
L
D
A
D
I
D
C
N
G
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.3
85.9
N.A.
40.4
41
N.A.
44.7
39.8
28
50.4
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
100
99.6
89.4
90.7
N.A.
58.9
59.5
N.A.
53.4
59.2
46.5
66.6
N.A.
N.A.
N.A.
49.5
N.A.
P-Site Identity:
100
93.3
93.3
66.6
N.A.
0
0
N.A.
40
0
13.3
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
13.3
13.3
N.A.
53.3
13.3
26.6
26.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
17
50
17
9
17
9
0
0
0
0
% A
% Cys:
0
0
0
9
34
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
17
0
25
0
17
17
25
9
9
9
34
0
42
42
% D
% Glu:
0
0
9
9
25
17
25
9
17
9
34
17
42
25
0
% E
% Phe:
0
0
0
0
9
0
0
0
25
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
9
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
25
0
0
0
25
% H
% Ile:
0
9
0
0
0
0
9
0
0
9
0
25
0
9
9
% I
% Lys:
0
25
25
0
25
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
50
0
9
0
0
9
0
9
17
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
25
0
9
9
9
0
% N
% Pro:
0
42
25
42
9
34
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
9
0
9
0
0
0
0
% Q
% Arg:
17
0
0
0
0
9
0
0
0
9
0
0
9
0
9
% R
% Ser:
9
0
25
0
0
0
0
34
9
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
25
9
0
0
0
0
0
0
0
25
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _