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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK6
All Species:
15.15
Human Site:
S51
Identified Species:
30.3
UniProt:
Q9Y257
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y257
NP_004814.1
313
33747
S51
R
A
Q
L
L
Q
R
S
P
C
V
A
A
P
A
Chimpanzee
Pan troglodytes
XP_524250
313
33801
S51
R
A
Q
L
L
Q
R
S
P
C
V
A
A
P
A
Rhesus Macaque
Macaca mulatta
XP_001106822
314
34300
S51
R
A
Q
L
L
Q
R
S
P
C
V
A
A
P
A
Dog
Lupus familis
XP_541645
313
34104
S51
R
E
E
L
L
R
R
S
P
C
V
A
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
O08581
336
38257
H67
K
R
R
F
L
E
E
H
E
C
L
S
E
P
Q
Rat
Rattus norvegicus
Q9Z2T2
336
38210
H67
K
R
R
F
L
E
E
H
E
C
L
S
E
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516092
322
34925
R76
E
A
R
A
R
G
A
R
E
R
G
E
G
T
K
Chicken
Gallus gallus
XP_419561
336
38076
H67
K
Q
R
F
L
V
E
H
A
C
L
S
E
Q
Q
Frog
Xenopus laevis
Q63ZI0
374
42700
K49
K
A
E
E
I
R
L
K
G
K
Y
N
I
S
S
Zebra Danio
Brachydanio rerio
NP_001025245
315
35059
S55
K
A
E
F
L
N
L
S
C
V
N
S
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
V44
Q
R
K
L
V
Q
R
V
R
E
K
L
K
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL25
443
49308
A119
N
F
H
R
S
K
T
A
P
A
M
A
A
I
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.3
85.9
N.A.
40.4
41
N.A.
44.7
39.8
28
50.4
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
100
99.6
89.4
90.7
N.A.
58.9
59.5
N.A.
53.4
59.2
46.5
66.6
N.A.
N.A.
N.A.
49.5
N.A.
P-Site Identity:
100
100
100
80
N.A.
20
20
N.A.
6.6
13.3
6.6
20
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
53.3
53.3
N.A.
13.3
40
40
40
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
9
0
0
9
9
9
9
0
42
42
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
9
59
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
25
9
0
17
25
0
25
9
0
9
25
0
0
% E
% Phe:
0
9
0
34
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
9
0
9
0
0
% G
% His:
0
0
9
0
0
0
0
25
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
42
0
9
0
0
9
0
9
0
9
9
0
9
0
17
% K
% Leu:
0
0
0
42
67
0
17
0
0
0
25
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
9
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
42
0
0
0
0
50
0
% P
% Gln:
9
9
25
0
0
34
0
0
0
0
0
0
0
9
25
% Q
% Arg:
34
25
34
9
9
17
42
9
9
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
42
0
0
0
34
0
9
9
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
9
17
0
% T
% Val:
0
0
0
0
9
9
0
9
0
9
34
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _