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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNK6 All Species: 18.18
Human Site: T42 Identified Species: 36.36
UniProt: Q9Y257 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y257 NP_004814.1 313 33747 T42 R L R A E L E T L R A Q L L Q
Chimpanzee Pan troglodytes XP_524250 313 33801 T42 R L R A E L E T L R A Q L L Q
Rhesus Macaque Macaca mulatta XP_001106822 314 34300 T42 Q L R A E L E T L R A Q L L Q
Dog Lupus familis XP_541645 313 34104 T42 R L R A E L E T L R E E L L R
Cat Felis silvestris
Mouse Mus musculus O08581 336 38257 K58 L L R Q E L R K L K R R F L E
Rat Rattus norvegicus Q9Z2T2 336 38210 K58 L L R Q E L R K L K R R F L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516092 322 34925 A67 R R R S R V R A V E A R A R G
Chicken Gallus gallus XP_419561 336 38076 K58 L L R Q E L G K L K Q R F L V
Frog Xenopus laevis Q63ZI0 374 42700 K40 Y E M R E E E K L K A E E I R
Zebra Danio Brachydanio rerio NP_001025245 315 35059 S46 S L K A D L S S L K A E F L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17185 329 36973 I35 A L E T E N E I L Q R K L V Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL25 443 49308 T110 P V R K S K P T I N F H R S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 86.3 85.9 N.A. 40.4 41 N.A. 44.7 39.8 28 50.4 N.A. N.A. N.A. 28.8 N.A.
Protein Similarity: 100 99.6 89.4 90.7 N.A. 58.9 59.5 N.A. 53.4 59.2 46.5 66.6 N.A. N.A. N.A. 49.5 N.A.
P-Site Identity: 100 100 93.3 80 N.A. 40 40 N.A. 20 40 26.6 40 N.A. N.A. N.A. 40 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 60 60 N.A. 46.6 53.3 53.3 73.3 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 42 0 0 0 9 0 0 50 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 75 9 50 0 0 9 9 25 9 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 34 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 9 0 0 0 0 9 0 % I
% Lys: 0 0 9 9 0 9 0 34 0 42 0 9 0 0 9 % K
% Leu: 25 75 0 0 0 67 0 0 84 0 0 0 42 67 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 9 % N
% Pro: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 25 0 0 0 0 0 9 9 25 0 0 34 % Q
% Arg: 34 9 75 9 9 0 25 0 0 34 25 34 9 9 17 % R
% Ser: 9 0 0 9 9 0 9 9 0 0 0 0 0 9 0 % S
% Thr: 0 0 0 9 0 0 0 42 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 9 0 0 9 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _