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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK6
All Species:
19.3
Human Site:
Y308
Identified Species:
38.6
UniProt:
Q9Y257
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y257
NP_004814.1
313
33747
Y308
S
A
S
S
H
T
D
Y
A
S
I
P
R
_
_
Chimpanzee
Pan troglodytes
XP_524250
313
33801
Y308
S
A
S
S
H
T
D
Y
A
S
I
P
R
_
_
Rhesus Macaque
Macaca mulatta
XP_001106822
314
34300
Y309
S
A
S
S
H
T
D
Y
A
S
I
P
R
_
_
Dog
Lupus familis
XP_541645
313
34104
Y308
T
A
D
S
H
P
D
Y
A
S
I
P
R
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O08581
336
38257
E330
A
S
Q
S
P
P
Y
E
D
G
S
A
D
H
_
Rat
Rattus norvegicus
Q9Z2T2
336
38210
E330
A
S
Q
S
P
P
Y
E
D
G
S
A
N
H
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516092
322
34925
Y317
F
P
P
V
H
A
N
Y
S
S
M
A
R
_
_
Chicken
Gallus gallus
XP_419561
336
38076
D331
S
Q
S
P
T
S
N
D
S
S
L
N
N
_
_
Frog
Xenopus laevis
Q63ZI0
374
42700
S319
V
S
H
Q
N
S
F
S
S
K
L
N
P
Q
Y
Zebra Danio
Brachydanio rerio
NP_001025245
315
35059
Y310
D
P
S
S
Q
V
S
Y
N
S
I
N
R
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
Q297
L
A
S
C
S
C
Y
Q
L
P
D
E
K
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL25
443
49308
L427
N
S
G
R
I
T
L
L
D
L
L
E
S
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.3
85.9
N.A.
40.4
41
N.A.
44.7
39.8
28
50.4
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
100
99.6
89.4
90.7
N.A.
58.9
59.5
N.A.
53.4
59.2
46.5
66.6
N.A.
N.A.
N.A.
49.5
N.A.
P-Site Identity:
100
100
100
76.9
N.A.
7.1
7.1
N.A.
30.7
23
0
46.1
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
84.6
N.A.
21.4
21.4
N.A.
53.8
53.8
40
46.1
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
42
0
0
0
9
0
0
34
0
0
25
0
0
0
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
34
9
25
0
9
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
17
0
0
0
17
0
0
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
17
0
0
0
0
0
% G
% His:
0
0
9
0
42
0
0
0
0
0
0
0
0
17
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
42
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
9
0
0
0
0
0
9
9
9
9
25
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
17
0
9
0
0
25
17
0
0
% N
% Pro:
0
17
9
9
17
25
0
0
0
9
0
34
9
0
0
% P
% Gln:
0
9
17
9
9
0
0
9
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
50
0
9
% R
% Ser:
34
34
50
59
9
17
9
9
25
59
17
0
9
9
0
% S
% Thr:
9
0
0
0
9
34
0
0
0
0
0
0
0
0
9
% T
% Val:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
25
50
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
75
% _