Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHKB All Species: 17.58
Human Site: S93 Identified Species: 38.67
UniProt: Q9Y259 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y259 NP_005189.2 395 45271 S93 S L P D H L P S V G E E P R E
Chimpanzee Pan troglodytes XP_001144399 395 45239 S93 S L P D H L P S V G E E P R E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848257 395 45274 S93 S L P D H L P S V G K E P R E
Cat Felis silvestris
Mouse Mus musculus O55229 394 45108 S93 S L P N H V P S V G G E P R E
Rat Rattus norvegicus O54783 394 45082 S93 S L P N H V P S M G G E P R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520038 436 47973 R105 P H E K N Q I R A S P E S L G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001093482 451 51710 P154 S L P D D V K P A G V E P R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54352 518 59544 D138 R V V P Q I E D R Y P A Q N A
Honey Bee Apis mellifera XP_624492 379 44310 R82 Y G Q I H G E R A L E G L I T
Nematode Worm Caenorhab. elegans P46558 371 42767 Q74 Y L L R I H R Q G P S H V F M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20485 582 66298 V164 M T N A I F K V E Y P K L P S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 90.3 N.A. 85.8 84.8 N.A. 38.9 N.A. N.A. 52.9 N.A. 20.6 44 27.3 N.A.
Protein Similarity: 100 99.7 N.A. 94.1 N.A. 92.9 92.1 N.A. 49.7 N.A. N.A. 68 N.A. 38 61.7 45.8 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 80 73.3 N.A. 6.6 N.A. N.A. 53.3 N.A. 0 13.3 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 13.3 N.A. N.A. 60 N.A. 13.3 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 28 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 37 10 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 19 0 10 0 28 64 0 0 46 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 10 0 0 0 10 0 0 10 55 19 10 0 0 10 % G
% His: 0 10 0 0 55 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 10 19 10 10 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 0 0 19 0 0 0 10 10 0 0 0 % K
% Leu: 0 64 10 0 0 28 0 0 0 10 0 0 19 10 0 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 10 19 10 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 0 55 10 0 0 46 10 0 10 28 0 55 10 0 % P
% Gln: 0 0 10 0 10 10 0 10 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 10 0 0 10 19 10 0 0 0 0 55 10 % R
% Ser: 55 0 0 0 0 0 0 46 0 10 10 0 10 0 10 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 10 10 0 0 28 0 10 37 0 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _