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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHKB
All Species:
22.73
Human Site:
T191
Identified Species:
50
UniProt:
Q9Y259
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y259
NP_005189.2
395
45271
T191
E
P
H
W
L
F
G
T
M
E
R
Y
L
K
Q
Chimpanzee
Pan troglodytes
XP_001144399
395
45239
T191
E
P
H
W
L
F
G
T
M
E
R
Y
L
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848257
395
45274
T191
E
P
H
W
L
F
G
T
M
E
R
Y
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
O55229
394
45108
T191
E
P
R
W
L
F
G
T
M
E
R
Y
L
K
Q
Rat
Rattus norvegicus
O54783
394
45082
T191
E
P
R
W
L
F
G
T
M
E
R
Y
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520038
436
47973
R203
E
S
R
R
R
R
K
R
R
Q
G
G
G
V
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001093482
451
51710
T252
E
P
K
W
L
F
G
T
I
D
R
Y
M
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54352
518
59544
T236
V
R
I
Y
G
N
K
T
D
L
L
I
D
R
K
Honey Bee
Apis mellifera
XP_624492
379
44310
I180
I
L
E
N
I
E
D
I
D
V
R
H
L
K
N
Nematode Worm
Caenorhab. elegans
P46558
371
42767
K172
G
G
G
D
Y
E
I
K
P
T
T
V
T
Y
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20485
582
66298
A262
S
E
R
K
N
G
S
A
C
W
Q
K
I
N
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
90.3
N.A.
85.8
84.8
N.A.
38.9
N.A.
N.A.
52.9
N.A.
20.6
44
27.3
N.A.
Protein Similarity:
100
99.7
N.A.
94.1
N.A.
92.9
92.1
N.A.
49.7
N.A.
N.A.
68
N.A.
38
61.7
45.8
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
66.6
N.A.
6.6
20
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
86.6
N.A.
26.6
33.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
19
10
0
0
10
10
0
% D
% Glu:
64
10
10
0
0
19
0
0
0
46
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
10
10
55
0
0
0
10
10
10
0
10
% G
% His:
0
0
28
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
10
0
10
0
10
10
10
0
0
10
10
0
0
% I
% Lys:
0
0
10
10
0
0
19
10
0
0
0
10
0
55
10
% K
% Leu:
0
10
0
0
55
0
0
0
0
10
10
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
46
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
10
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
55
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
64
% Q
% Arg:
0
10
37
10
10
10
0
10
10
0
64
0
0
10
0
% R
% Ser:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
64
0
10
10
0
10
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% V
% Trp:
0
0
0
55
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
55
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _